The negative fitness consequences of close inbreeding are widely recognized, but predicting the long-term effects of inbreeding and genetic drift due to limited population size is not straightforward. As the frequency and homozygosity of recessive deleterious alleles increase, selection can remove (purge) them from a population, reducing the genetic load. At the same time, small population size...

OBJECTIVE AND METHOD To inform the classification of bulimic-type eating disorders not meeting formal diagnostic criteria for bulimia nervosa (BN), levels of eating disorder psychopathology and functional impairment associated with subjective and objective bulimic episodes (SBEs and OBEs) and purging and nonpurging methods of weight control were examined in a large community-based sample of wom...

OBJECTIVES The relationship between emotional states and eating behaviors is complex, and emotional eating has been identified as a possible factor triggering binge eating in bulimia nervosa (BN) and binge eating disorder. Few studies considered emotional eating in patients with anorexia nervosa. METHODS The present study evaluated the clinical correlates of emotional eating in 251 eating-dis...

To determine the risk factors for hospitalization in 0 to 24-month-old children with acute diarrhea, a retrospective case-control study was done at the Diarrheal Diseases Training and Treatment Center, where all the cases are managed according to World Health Organization (WHO) criteria. For each hospitalized patient, the next two consecutive admissions were enrolled as the control group. Clini...

Equality data bases are important in facilitating proofs of equality between terns. They are useful in the implementation of code optimizers [2], program verifiers [7,9], theorem provers [I], and symbolic execution systems [S]. In these applications the typical operations are determining whether or not two terms are known to be equal and updating the data base to include a new equality. Some so...

In grid computing, trust has massive significance. There is lot of research to propose various models in providing trusted resource sharing mechanisms. The trust is a belief or perception that various researchers have tried to correlate with some computational model. Trust on any entity can be direct or indirect. Direct trust is the impact of either first impression over the entity or acquired ...

BACKGROUND The accumulation of deleterious mutations can drastically reduce population mean fitness. Self-fertilization is thought to be an effective means of purging deleterious mutations. However, widespread linkage disequilibrium generated and maintained by self-fertilization is predicted to reduce the efficacy of purging when mutations are present at multiple loci. METHODOLOGY/PRINCIPAL F...

In an inbred population, selection may reduce the frequency of deleterious recessive alleles through a process known as purging. Empirical studies suggest, however, that the efficacy of purging in natural populations is highly variable. This variation may be due, in part, to variation in the expression of inbreeding depression available for selection to act on. This experiment investigates the ...