PURPOSE To discuss the indications and therapeutic outcomes of synovectomy, debridement, and continuous irrigation for the treatment of pyogenic arthritis caused by intra-articular injection used in the treatment of osteoarthritis of the knee. METHODS Records of 41 patients with infectious arthritis of the knee who presented to our hospital from 1981 were reviewed. 11 of them had a history of...

BACKGROUND Intraarticular injections for the local treatment of osteoarthritis are widely used in the office or hospital setting. Septic arthritis is a potential catastrophic complication of intraarticular injection, as bacterial arthritis of any cause is associated with up to 15% mortality and residual impairment of joint function in up to 50% of survivors. There is lack of evidence regarding ...

Pyogenic myositis is a primary subacute deep bacterial infection of the skeletal muscle. It is a rare condition that is usually regarded as a tropical disease being common in parts of Africa and the South Pacific. It has been reported in patients of all ages but is predominantly a condition afflicting children and young adults. The development of pyogenic myositis is thought to arise from a tra...

Pyogenic sacroiliitis is a rare disease entity, comprising only 1% to 2% of cases of osteomyelitis and septic arthritis. Clinical symptoms and signs are usually non-specific and may result in delayed diagnosis. This report is of a 15-year-old girl with pyogenic sacroiliitis and iliacus abscess without any predisposing factors. Various imaging modalities, including computed tomography and magnet...

PAPA syndrome (Pyogenic Arthritis, Pyoderma gangrenosum, and Acne) is an autosomal dominant, hereditary auto-inflammatory disease arising from mutations in the PSTPIP1/CD2BP1 gene on chromosome 15q. These mutations produce a hyper-phosphorylated PSTPIP1 protein and alter its participation in activation of the "inflammasome" involved in interleukin-1 (IL-1β) production. Overproduction of IL-1β i...

Pyogenic sacroiliitis accounts for 1-2% of all cases of septic arthritis with less than 200 cases reported in the English literature since the beginning of the twentieth century. Cultures of joint fluid usually grow Staphylococcus aureus. Prognosis is excellent; however, diagnosis may be difficult due to rarity of disease and non-specific signs, symptoms, and physical findings. Magnetic resonan...

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