introduction: antibiotic- associated diarrhea is a common problem in pediatric population. there is growing interest in probiotics, probiotics and synbiotics for prevention of this complication because of their worldwide availability as dietary supplements. the aim of this study was to assess the efficacy of a synbiotic mixture in prevention of antibiotic- associated diarrhea.   materials and m...

Precipitation behaviour of wrought Al-6Mg alloys with ternary scandium and quaternary zirconium and titanium has been studied. Hardness measurements and resistivity studies are employed to assess the precipitation behaviour of scandium doped Al-6Mg alloy without or with quaternary additions of zirconium and titanium. Further, the kinetics of precipitations are studied by differential scanning c...

Abstract Background The current study describes the use of central composite design for multivariate optimization resolution and retention time, taking into account different critical method parameters like organic phase, pH, flow rate, wavelength risk assessment. chromatographic assay most effective anti-viral regimen (EPCLUSA, DARVONI, HARVONI) was developed. An experimental presented by sequ...

Introduction Pre-Quaternary paleoclimate modeling is the science of simulating climate change over the earliest 99.9% of Earth’s history using numerical models of the climate system. The record of pre-Quaternary climate documents enormous climate swings with global ice-covered and ice-free end members. A number of climate factors shaped Quaternary and pre-Quaternary paleoclimate on timescales r...

Many properties of chemicals depend on their stereochemistry. Among these, the effects of stereoisomerism on percutaneous absorption of drugs are not well studied. We have previously shown that permeation of tretinoin and isotretinoin (two geometric isomers) through hydrophilic enhancers-treated rat skin is stereoselective. As, depending on their lipophilicity, penetration enhancers can change ...

Many properties of chemicals depend on their stereochemistry. Among these, the effects of stereoisomerism on percutaneous absorption of drugs are not well studied. We have previously shown that permeation of tretinoin and isotretinoin (two geometric isomers) through hydrophilic enhancers-treated rat skin is stereoselective. As, depending on their lipophilicity, penetration enhancers can change ...

â â â  parsian alluvial fan system is a part of asyab-kharabeh fluvial system that response it to quaternary climate changes is the main goal of this study. for this aim, climatic proxies and traces in alluvial fan structure were investigated base d o n four categories: aggradation and degradation phases, debris flows, size changes in deposited materials and formation of alluvial fan tufas. pri...

Introduction Pre-Quaternary paleoclimate modeling is the science of simulating climate change over the earliest 99.9% of Earth’s history using numerical models of the climate system. The record of pre-Quaternary climate documents enormous climate swings with global ice-covered and ice-free end members. A number of climate factors shaped Quaternary and pre-Quaternary paleoclimate on timescales r...

the article analyzes literature problems using as a parameter the quaternary prevention concept, introducing guidelines to have good shared decisions that avoid overdiagnosis and overtreatment and improve the quality of life. the author proposes a four-step approach: reliable evidence, awareness about populations profile, independent research analysis, and an understandable format by ordinary p...