Extracts of the Quillaja saponaria tree contain natural surfactant molecules called saponins that very efficiently stabilize foams and emulsions. Therefore, such extracts are widely used in several technologies. In addition, saponins have demonstrated nontrivial bioactivity and are currently used as essential ingredients in vaccines, food supplements, and other health products. Previous prelimi...

Saponins are natural detergents (surfactants) found in a variety of plants. The two major commercial sources are desert plants: Yucca schidigera from Mexico and Quillaja saponaria from Chile. Yucca saponins have a steroid nucleus, whereas Quillaja saponins are triterpenoid in structure. Saponins contain a lipophilic nucleus (steroid or triterpenoid) and one or more water– soluble carbohydrate s...

The effect of two different commercial products Quillaja saponaria saponin extract on mortality the free-living copepodite stage sea-lice Caligus rogercresseyi were assessed in vitro. Parasites exposed for 24 hr to concentrations extracts and then observed until 30 non-Quillaja media. EC50 EC90 evaluated at hr. High mortalities copepodites obtained higher doses (500 ppm) both extracts. Higher u...

Saponins have been considered as promising natural substances for mitigating methane emissions from ruminants. However, studies reported that addition of saponin-rich sources often arrived at contrasting results, i.e. either it decreased methane or it did not. The aim of the present study was to assess ruminal methane emissions through a meta-analytical approach of integrating related studies f...

objective(s): the purpose of this study was preparation and evaluation of plga nanospheres containing the influenza virus and different adjuvants, quillaja saponin (qs) and cpg-odn.   materials and methods: nanospheres were prepared using the double emulsion-solvent evaporation method. the morphological and physicochemical properties were studied by scanning electron microscopy (sem), determina...

The purpose of the study was to compare cytotoxicity two Quillaja saponaria bark saponin (QBS) mixtures against lung cell lines: normal MRC-5 fibroblast line and tumor A-549 epithelial cells lungs’ alveoli. study, performed both at a macro-scale in dedicated microfluidic device, showed that QBS more toxic abundant cholesterol (MRC-5). mixture with higher fraction found be cytotoxic towards line...

Saponins are detergent-like substances showing antibacterial as well as anticancer potential. In this study, the effects of saponins from Quillaja saponaria were analyzed against prokaryotic and eukaryotic cells. Multidrug-resistant clinical E. coli strains were isolated from human urine. As eukaryotic cells, the CHO-K1 cell lines were applied. Antibacterial effect of ampicillin, streptomycin, ...

leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems. alginate microspheres as an antigen delivery system and quillaja saponins (qs) as an immunoadjuvant have been used to enhance the immune response against autoclaved leishmania major (alm). microspheres were prepared by an emulsification technique and characterized for size, encapsulatio...

This study investigated the effects of garlic oil (0.25 g/L), nitrate (5 mM), and quillaja saponin (0.6 g/L), alone and in binary or ternary combinations, on methanogenesis, rumen fermentation, and abundances of select microbial populations using in vitro rumen cultures. Potential adaptation to these compounds was also examined by repeated transfers of the cultures on alternate days until day 1...