نتایج جستجو برای: quinazolinones
تعداد نتایج: 182 فیلتر نتایج به سال:
The need for new classes of antibacterials is genuine in light the dearth clinical options treatment bacterial infections. prodigious discoveries antibiotics during 1940s to 1970s, a period wistfully referred as Golden Age Antibiotics, have not kept up face emergence resistant bacteria past few decades. There has been renewed interest old drugs, repurposing existing and pairing synergistic or a...
wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. deoxyvasicinone which wa...
Quinazolinones is an important chemical synthesis with different physiological significance and pharmacological utility. Reaction of anthranilic acid with benzoyl chloride in pyridine yielded 2-phenyl4H-benzo[d][1,3]oxazin-4-one, which on condensation reaction with the tryptophan in glacial acetic acid afforded 3-(1H-indol-3-yl)-2-(4-oxo-2-phenylquinazolin-3(4H)-yl) propanoic acid (2). Treatmen...
member of the transmembrane G-protein coupled receptors family comprising d , k and m opioid receptors. Its original homology cloning and the isolation from brain extracts of the endogenous ligand, the heptadecapeptide nociceptin (NC), gave rise to a great interest in clarifying its physiological functions. The receptor, distributed in both central and peripheral nervous systems and in non-neur...
quinazolinones are heterocyclic and water insoluble compounds with various pharmacological and biological characteristics (antibacterial, antiswelling, antifungal, parkinson and etc.). they are used for treatment hiv and cancer. this study investigated the effects of 4(3h) quinazlonones-2-ethyl-2-phenyl ethyl (qepe) as a new quinazolinons compounds on the spleen and immunocompetent cells of new...
Millipedes (Diplopoda) are a diverse group of arthropods that include 16 orders represented by approximately 12,000 species in 145 families (Sierwald & Bond, 2007). In 11 of these orders, millipedes are protected from predators by chemical defenses produced in glands that vary in number among orders and are located laterally or mid-dorsally in the diplosegments (Eisner et al., 1978; Hopkin & Re...
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