BACKGROUND An increase of plasma kynurenine concentrations, potentially bioactive metabolites of tryptophan, was found in subjects with obesity, resulting from low-grade inflammation of the white adipose tissue. Bariatric surgery decreases low-grade inflammation associated with obesity and improves glucose control. OBJECTIVE Our goal was to determine the concentrations of all kynurenine metab...

EXCITATORY AMINO ACIDS IN EPILEPSY 133 5.1. Background 133 5.1.1. Classification of excitatory amino acid receptors 133 5.2. Role of Excitatory Amino Acids in Transmission of Hyperactivity 133 5.3. Role of excitatory amino acids in Primary Events 135 5.3.1. Convulsions induced by glutamate 135 5.3.2. Excitotoxic action 135 5.3.3. Neurotoxic lesions as epileptic foci 136 5.3.4. Quinolinic acid 1...