نتایج جستجو برای: quinone

تعداد نتایج: 5334  

Journal: :Journal of Biological Chemistry 2008

Journal: :Frontiers in bioscience : a journal and virtual library 2000
A Begleiter

Quinone-containing alkylating agents are a class of chemical agents that have received considerable interest as anticancer drugs. These agents contain a quinone moiety that can be reduced and an alkylating group that can form covalent bonds with a variety of cellular components. The oxidation state of the quinone element can modulate the activity of the alkylating element, and reduction of the ...

A. Mashayekhi-Sardoo F. Farhadi Gh. Karimi H. Mashayekhi-Sardoo* P. Shoae-Hagh

Background and objectives: Nigella sativa is a delicate floral vegetable belonging to Ranunculaceae family. Thymoquinone (TQ) is the dominant active component in Nigella sativa seed oil which has a variety of pharmacological properties such as antioxidant, anticancer, anti-inflammatory and analgesic activities. However, TQ is a quinone derivative, which may le...

Journal: :Molecules 2009
Sevket Hakan Ungören

Novel naphtho[2,3-f]quinoxaline-2,7,12(1H)-trione and anthra-9,10-quinone dyes were synthesized in good yield from furan-2,3-diones using 1,2-diaminoanthra-9,10-quinone and 1,4-diaminoanthra-9,10-quinone. The chromophores were characterized by molecular spectroscopy methods.

Journal: :iranian journal of public health 0
s eshraghi ian c hancock e williams

the methylotrophic thermo tolerant actinomycete strain 381, was isolated from a compost sample, assimilated methanol during growth. methanol dehydrogenase could not be detected in cell extracts using dye-linked assays in the absence of nad+. dichlorophenol-indophenol-linked methanol oxidation was detected in broken cell suspensions in the presence of nad+ and the absence of cyanide. taxonomic s...

2006
Garth Powis Ernest M. Hodnett Kenneth S. Santone Kevin Lee Deborah C. Melder

Quinone(di)iinines are nitrogen analogues of quiñonesin which one or both quinone oxygens are replaced by an ¡minogroup. A series of quinone(di)imines with antitumor activity has been studied for its in vitro chemical reactivity, metabolism, acute toxicity to primary cultured rat hepatocytes, and growth-inhibitory activity with Chinese hamster ovary (CHO) cells. The quinone(di)iniines exhibit...

2012

F r a n z D a l l a c k e r * , G e r m a n u s R e i c h r a t h u n d G e r a r d S c h n a c k e r s Institut für Organische Chemie der Technischen Hochschule Aachen, Prof.-Pirlet-Straße 1, D-5100 Aachen Z. Naturforsch. 34b, 624-632 (1979); eingegangen am 13. November 1978 5,6-Dimethyl-l,3-benzodioxole-4,7-quinone, 6,7-Dimethyl-l,4-benzodioxan-5,8-quinone, 7,8 -Dimethyl 3,4 -dihy dro 2 H -1,...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2013
Yasuhiro Ishihara

Quinones are widely distributed in nature, and some quinone compounds are used as therapeutic agents such as anti-cancer, anti-malarial or anti-bacterial drugs. However, their therapeutic use is limited in some cases because the use of most quinones is accompanied by adverse effects derived from their cytotoxicity, especially for hepatocytes. Two mechanisms have been proposed to explain quinone...

Journal: :Journal of the American Chemical Society 2008
Jean-Philip Lumb Kevin C Choong Dirk Trauner

A concise synthesis of rubioncolin B is described, which features an unprecedented intramolecular Diels-Alder reaction involving an ortho-quinone methide and a naphthofuran moiety. The ortho-quinone methide is generated through a surprisingly facile tautomerization of a para-quinone.

Ali Mazloomifar Ali Parsa Maryam Helmi

In this study, the electrochemical mechanism of catechol in presence and absence of nitrite ion, is investigated in phosphate buffer medium (pH=7) using platinum electrode through cyclic voltammetry method in various scan rates. Electrochemical oxidation of catechol showed how quinone has changed to o-benzoquinone and also how o-benzoquinone has reacted with nitrite ion and potential scan rate ...

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