Bacteria use a process of chemical communication called quorum sensing to assess their population density and to change their behavior in response to fluctuations in the cell number and species composition of the community. In this work, we identified the quorum-sensing-regulated proteome in the model organism Vibrio harveyi by bio-orthogonal non-canonical amino acid tagging (BONCAT). BONCAT en...

Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced by neighboring bacteria. They are widespread: over 100 morphologically and genetically distinct species of eubacteria are known to use quorum sensing to control gene expression. This diversity suggests the potential to use natural protein variants to engineer parallel, input-specific, cell-cell communicati...

Signaling mechanisms that govern physiological and morphological responses to changes in cell density are common in bacteria. Quorum sensing, as such signal transduction processes are called, involves the production of, release of, and response to hormone-like molecules (autoinducers) that accumulate in the external environment as the cell population grows. Quorum sensing is found in a wide var...

The reconstruction of an unknown temporal-spatial profile from participatory sensing data poses a number of challenges due to uncoordinated user movement and possibly low user involvement. This paper considers the problem of reconstructing such a profile from participatory sensing data by exploiting the theory of compressive sensing. In particular we study the impact of the number of users and ...

Understanding of the intracellular molecular machinery that is responsible for the complex collective behavior of multicellular populations is an exigent problem of modern biology. Quorum sensing, which allows bacteria to activate genetic programs cooperatively, provides an instructive and tractable example illuminating the causal relationships between the molecular organization of gene network...

Signaling mechanisms that govern physiological and morphological responses to changes in cell density are common in bacteria. Quorum sensing, as such signal transduction processes are called, involves the production of, release of, and response to hormone-like molecules (autoinducers) that accumulate in the external environment as the cell population grows. Quorum sensing is found in a wide var...

Bacterial conversations: talking, listening and eavesdropping. An introduction 1115 I. Joint, J. Allan Downie & P. Williams Look who’s talking: communication and quorum sensing in the bacterial world 1119 P. Williams, K. Winzer, W. C. Chan & M. Cámara Cell–cell communication in the plant pathogen Agrobacterium tumefaciens 1135 C. E. White & S. C. Winans Quorum-sensing regulation in rhizobia and...

Quorum sensing (QS) regulates the behavior of bacterial populations and promotes their adaptation and survival under stress. As QS is responsible for the virulence of vast majority of bacteria, quorum quenching (QQ), the interruption of QS, has become an attractive therapeutic strategy. However, the role of QS in stress tolerance and the efficiency of QQ under stress in bacteria are seldom expl...

The abundance of quorum quenching (QQ) activity was evaluated in cultivable bacteria obtained from oceanic and estuarine seawater and compared with the frequency of QQ enzyme sequences in the available marine metagenomic collections. The possible role of the high QQ activity found among marine bacteria is discussed.

“Quorum Sensing” has been identified as one of the most consequential microbiology discoveries of the last 10 years. Using Quorum Sensing bacterial colonies synchronize gene expression and phenotype change allowing them, among other things, to protect their niche, coordinate host invasion and bio-film formation. In this contribution we briefly describe the elementary microbiology background and...