PURPOSE The aim of this paper is to report thermal dosimetry characteristics of external deep regional pelvic hyperthermia combined with intravesical mitomycin C (MMC) for treating bladder cancer following transurethral resection of bladder tumour, and to use thermal data to evaluate reliability of delivering the prescribed hyperthermia dose to bladder tissue. MATERIALS AND METHODS A total of...

Thermal intervention is a potent sensitizer of cells to chemo- and radiotherapy in cancer treatment. Glioblastoma multiforme (GBM) potential clinical target, given the cancer’s aggressive nature resistance current treatment options. This drives research into optimization algorithms for planning as well radiofrequency (RF) applicator design delivery. In this work, nine clinically realistic GBM t...

The finite difference time domain method is used to calculate the specific absorption rate (SAR) due to a butterfly surface coil in a realistic tissue model of the leg. The resulting temperature distribution and temperature changes are found using a finite difference solution to the bioheat transfer equation. Reasonable agreement is found between predicted temperature changes and those measured...

The use of mathematical models to study complex systems such as physical and biological phenomena allows understanding their behavior, specifically regarding variables parameters that are difficult obtain. Additionally, studying optimization techniques has made it possible approximate the characteristics these by correlating numerical simulations experimentation. Radiofrequency hyperthermia the...