Radiofrequency (RF) catheter ablation is the preferred choice for the treatment of symptomatic reentrant arrhythmias associated with accessory pathways or dual atrioventricular conduction. The mechanism of irreversible tissue injury by the RF catheter ablation is primarily thermally mediated [1,2]. The myocardial cellular electrophysiological effects of hyperthermia muscle have been recently ou...

PURPOSE The purpose of this study was to assess the pain relief in patients with unresectable and recurrent colorectal cancer treated with radiation plus 8 MHz radiofrequency-capacitive regional hyperthermia and to identify predictors of the good outcome. METHODS Between February 1986-May 2003, 41 patients with primarily unresectable and recurrent colorectal cancer that caused pain were treat...

Hyperthermia also called thermal therapy or thermotherapy is a type of cancer treatment in which body tissue is exposed to high temperatures. Research has shown that high temperatures can damage and kill cancer cells, usually with minimal injury to normal tissues. Otherwise, ablation or high temperature hyperthermia, including lasers and the use of radiofrequency, microwaves, and high-intensity...

BACKGROUND Capacitive radiofrequency (RF) hyperthermia suffers from excessive temperature rise near the electrodes and poorly localized heat transfer to the deep-seated tumor region even though it is known to have potential to cure ill-conditioned tumors. To better localize heat transfer to the deep-seated target region in which electrical conductivity is elevated by nanoparticle mediation, two...

The clinical application of hyperthermia in the treatment of deep-seated tumors remains an empirical science. The pleomorphic nature of the neoplasms and the great diversity in the anatomy and physiology of the individual tumor locations make the treatment of nearly every neoplasm a unique challenge. A wide variety of devices is required, both for the administra tion of hyperthermia and for the...

PURPOSE To investigate the technical feasibility of using ultrasound-guided intratumoral radiofrequency hyperthermia (RFH) to enhance local chemotherapy of rat orthotopic pancreatic cancers. MATERIALS AND METHODS Orthotopic pancreatic cancer masses were established by inoculating luciferase/mCherry labeled-pancreatic cancer cells into the pancreatic tails of Lewis model rats via a laparotomy ...

Hyperthermia is an experimental/adjuvant therapeutic modality for cancer. Combining hyperthermia with the non-invasive metabolic studies using magnetic resonance (MR) is an interesting area of research and can provide useful information. In this paper, feasibility of using the same radio frequency source for carrying out combined hyperthermia and MR studies is demonstrated. A conventional RF hy...