Radiotherapy following breast conservation is routine in the treatment of breast cancer. This creates a large demand for radiotherapy services with implicit cost effects and potential morbidity to patients. Radiotherapy is administered to decrease local recurrence, but is radiotherapy required for all breast cancers? A literature search using the Medline and Ovid databases was conducted between...

AIM To define the best sequence of radiotherapy and chemotherapy for inoperable stage III non-small cell lung (NSCL) tumours. MATERIALS AND METHODS A systematic review was performed on the clinical results of radiotherapy, combined or not with chemotherapy, for inoperable NSCL cancer stage III. The mean median survival time (MST) and mean overall survival (OS) percentages were derived for rad...

OBJECTIVE The objective was to analyze the outcomes of the patients, who received salvage radiotherapy for incidentally discovered cervical cancer following simple hysterectomy, and to identify the influence of intracavitary radiotherapy on treatment outcomes. METHODS Data from 117 patients with occult cervical cancer who underwent simple hysterectomy followed by salvage radiotherapy from Sep...

Introduction: Lower limb lymphedema (LLL) is one of the most disabling side effects surgical and radiotherapy treatment for gynecological cancers (carcinoma cervix, carcinoma ovary, endometrium, vulva). The incidence varies in patients undergoing surgery. This prospective study aims to determine lower after surgery malignancies.Methodology: A total 512 subjects who undergo malignancies departme...

Abstract PURPOSE To investigate the effect of radiotherapy and surgery in patients with lung cancer brain metastases (BMs) poor prognosis factors. METHODS We analyzed retrospectively 714 BMs. A 1:1 propensity score matching (PSM) was performed to balance potential confounders. Analyses overall survival (OS) risk factors for OS were assessed by log-rank test Cox proportional hazard model. RESULT...

BACKGROUND To conduct a comprehensive review whether chemotherapy to radiotherapy after surgical resection could improve the loco regional control and survival compared with postoperative radiotherapy alone. METHODS A comprehensive search of PubMed for relevant studies comparing patients with advanced squamous cell carcinoma of the head and neck undergoing chemoradiotherapy or radiotherapy al...

BACKGROUND The use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred radiotherapy (given only when a PTM developed) in a suitably powered trial. METHODS We did a multicentre, open-label, phase 3, randomised control...

Introduction: Successful radiotherapy requires the precise application of a radiation dose to cancerous tissue, which can be achieved by the design of proper treatment methods by radiotherapy physicists. Tasks performed by radiotherapy physicists include verifying the accuracy of dose calculations, correct treatment planning and the proper functioning of accelerators. They are...

OBJECTIVE To know the incidence of vesicourethral anastomotic stricture in patients with prostate cancer treated with radical prostatectomy. Our secondary aim was to verify if postoperative radiotherapy increases the risk of presenting anastomotic stricture. MATERIALS AND METHODS We retrospectively checked the clinical records of patients that had undergone radical prostatectomy as their prim...

Purpose. To compare the impact of prognostic factors of patients treated with definitive radio(chemo)therapy versus patients treated with surgery and postoperative radiotherapy for squamous cell carcinoma of the oro- and hypopharynx. Patients and Methods. 162 patients treated with definitive radiotherapy and 126 patients treated with postoperative radiotherapy were retrospectively analysed. The...