Relative adrenal insufficiency (RAI) was demonstrated in patients with cirrhosis and liver failure. A relationship appears to exist between the severity of the liver disease and the presence of RAI. Neither the mechanism nor the exact prevalence of RAI is fully understood. There is though a hypothesis that low high-density lipoprotein (HDL) levels in this group of patients may be responsible fo...

I n t e r v e n t i o n All patients received the short corticotropin test (250 μg of tetracosactrin intravenously) for diagnosis of relative adrenal insufficiency (RAI), defined as an increase in cortisol level of ≤ 248.31 nmol/L (9 μg/dL). Subsequently, patients were allocated to treatment with corticosteroids (n = 150 [including in retrospect 114 with RAI]) or placebo (n = 149 [including in ...

Functional thyroid carcinoma is an unusual cause of thyrotoxicosis. We describe the clinical presentation and treatment of a patient with thyrotoxicosis due to functional thyroid carcinoma and Graves disease, and discuss potential mechanisms causing the thyrotoxicosis. A 79-year-old woman with a remote history of hemithyroidectomy and current hyperthyroidism came to the hospital with upper and ...

UNLABELLED This study is a retrospective analysis of 124 differentiated thyroid cancer patients who underwent dosimetric evaluation using MIRD methodology over a period of 15 y. The objectives of the study were to demonstrate the clinical use of dosimetry-guided radioactive iodine ([RAI] (131)I) treatment and the safe and effective application of a 3-Gy bone marrow (BM) dose in patients with di...

The incidence of thyroid cancer has increased in the past few decades. Most patients with follicular cell–derived tumors present with well-differentiated carcinomas, and they have an excellent prognosis following treatment. Between 10% and 15% of tumors will mutate into more aggressive variants, such as tall-cell carcinoma and insular carcinoma. Some patients will present with poorly differenti...

Coordinated attention to information from multiple senses is fundamental to our ability to respond to salient environmental events, yet little is known about brain network mechanisms that guide integration of information from multiple senses. Here we investigate dynamic causal mechanisms underlying multisensory auditory-visual attention, focusing on a network of right-hemisphere frontal-cingula...

PATIENT Female, 11 FINAL DIAGNOSIS: Thyroid storm Symptoms: Diarrhea • tachycardia • tachypnea • tremor • wheezing MEDICATION - Clinical Procedure: - Specialty: - OBJECTIVE Rare disease. BACKGROUND A growing number of pediatric endocrinologists treat Graves disease with radioactive iodine (RAI) therapy due to the typically definitive nature of I-131 therapy. Given the published benefits a...

We propose the recursive autonomy identification (RAI) algorithm for constraint-based (CB) Bayesian network structure learning. The RAI algorithm learns the structure by sequential application of conditional independence (CI) tests, edge direction and structure decomposition into autonomous sub-structures. The sequence of operations is performed recursively for each autonomous substructure whil...

BACKGROUND There is a high mortality in infants with right atrial isomerism (RAI). However, less is known about outcome in older children with RAI. This study sought to evaluate those patients with RAI who survived older than 3 years of age without surgical intervention. RESULTS A total of 33 consecutive patients (20 males) were enrolled in the study, mean age 6 years (range 3-32). None of th...