ftr-raman spectra of human dental enamel, both laser-irradiated and untreated, are reported. spectra are compared with hydroxyapatite. it is evident that unlike the co2 laser, the nd/yag laser does not induce any chemical change in dental enamel.

surface-enhanced raman spectroscopy (sers) is a promising tool in the analytical science because it provides good selectivity and sensitivity without the labeling process required by fluorescence detection. this technique consists of locating the target analyte on nanometer range of roughed au-nanoparticles. the presence of the metal nanoparticles provides a tremendous enhancement to the result...

Raman spectroscopy was developed by C. V. Raman (Figure 1) in 1928, but until recently has been plagued by weak Raman scattering responses compared to strong, interfering, Rayleigh scattering, plus fluorescence interferences. Developments over the past 15 years have permitted Raman spectroscopy to become more useful and easier to use. With these developments, forensic analysis by Raman spectros...

Raman spectroscopy is emerging as a promising and novel biophotonics tool for non-invasive, real-time diagnosis of tissue and cell abnormalities. However, the presence of a strong fluorescence background is a key issue that can detract from the use of Raman spectroscopy in routine clinical care. The review summarizes the state-of-the-art methods to remove the fluorescence background and explore...

Raman spectroscopy is a unique optical technique that can probe the changes of vibrational modes of biomolecules associated with tissue premalignant transformation. This study evaluates the clinical utility of confocal Raman spectroscopy over near-infrared (NIR) autofluorescence (AF) spectroscopy and composite NIR AF/Raman spectroscopy for improving early diagnosis of cervical precancer in vivo...

Raman spectroscopy is based on analysis of inelastically scattered light. This technique has a wide range of uses in chemistry, solid-state physics and other fields. Raman spectroscopy can distinguish between molecules and can identify them by their characteristic spectra. In this seminar I will discuss instrumentation required for Raman spectroscopy in medical applications, followed by specifi...

Over the last decade Raman spectroscopy has become established as a physicochemical technique for the rapid identification of microbes. This powerful analytical method generates a spectroscopic fingerprint from the microbial sample, which provides quantitative and qualitative information that can be used to characterize, discriminate and identify microorganisms, in both bacteria slurry and at t...

Raman spectroscopy such as spontaneous Raman spectroscopy, coherent anti-stokes Raman spectroscopy, and stimulated Raman gain spectroscopy are widely used in physics, chemistry and biology fields for investigations of vibrational modes. To our best knowledge, very few applications of Raman spectroscopy for the in-vitro and invivo patient medical diagnostics have been reported because of low sig...

Currently, positive endoscopic biopsy is the standard criterion for gastric cancer diagnosis but is invasive, often inconsistent, and delayed although early detection and early treatment is the most important policy. Raman spectroscopy is a spectroscopic technique based on inelastic scattering of monochromatic light. Raman spectrum represents molecular composition of the interrogated volume pro...

Background and Aims: Mesenchymal stem cells (MSCs) are a preferred cell source for the generation of hepatocyte-like cells in regenerative medicine. They can be isolated from different sources, including adipose tissues. The Raman spectroscopy approach was evaluated for quick and efficient identification of MSCs differentiation status and a broader perspective on cell differentiation. Material...