Background: Among manuscripts submitted to biomedical journals, randomized controlled trials (RCTs) form the backbone of evidence-based medicine. Hence, their protocol should be designed rigorously and their results should be reported clearly. To improve the quality of RCT reporting, researchers developed the CONSORT Statement in 1996 and updated it in 2010. This study was designed to assess th...

background:  the primary aim of this study was to determine predictors of missed research appointments in a prospective  andomized placebo injection-controlled trial with evaluations 1 to 3 and 5 to 8 months after enrollment.   methods:  this study represents a secondary use of data from 104 patients that were enrolled in a prospective randomized  ontrolled trial of dexamethasone versus lidocai...

This study evaluated the efficacy and long-term effectiveness of intensive short-term dynamic psychotherapy (ISTDP) in the treatment of patients with DSM-IV personality disorders (PD). Twenty-seven patients with PD were randomized to treatment with ISTDP or a minimal-contact, delayed-treatment control condition. ISTDP-treated patients improved significantly more than controls on all primary out...

BACKGROUND There is strong research evidence for falls prevention among older people in the community setting, although most is from Western countries. Differences between countries (eg sunlight exposure, diet, environment, exercise preferences) may influence the success of implementing falls prevention approaches in Asian countries that have been shown to be effective elsewhere in the world. T...

BACKGROUND Publication bias and other reporting bias have been well documented for journal articles, but no study has evaluated the nature of results posted at ClinicalTrials.gov. We aimed to assess how many randomized controlled trials (RCTs) with results posted at ClinicalTrials.gov report statistically significant results and whether the proportion of trials with significant results differs ...

ANAL CANAL CARCINOMA IS AN uncommon malignancy in the United States. Among 1 437 180 new cancer diagnoses projected for the year 2008, approximately 5070 will be new cases of anal canal carcinoma. Anal canal carcinoma has a unique clinical biology that can be distinguished from all other gastrointestinal cancers. It is mostly a local-regional cancer, with a metastatic potential in only 15% of p...

Objectives: To determine if a modified version of the cross body stretch that incorporates scapular stabilization immediately following a bout of pitching will increase passive shoulder range of motion more than the standard cross body stretch in male collegiate baseball players. Background: Overhead athletes, mainly baseball players, often exhibit pathologic gross internal rotation deficit (pG...

Background: Concept-based Indexing is purported to provide more granular data representation for clinical records"'2 This implies that a detailed clinical terminology should be able to provide improved access to clinical records. To date there is no data to show that a clinical reference terminology is superior to a precoordinated terminology in its ability to provide access to the clinical rec...

The high prevalence and diversity of longer-term problems experienced by patients with stroke and their carers has long been recognized, but they remain poorly addressed by existing services. Postdischarge contact with therapy services is associated with improved outcomes. However, these interventions are generally time limited and have little effect on psychosocial outcome. National guidelines...

Correction Contact me if this article is corrected. http://jama.ama-assn.org/cgi/content/full/jama;294/23/2973 Correction is appended to this PDF and also available at Citations Contact me when this article is cited. This article has been cited 73 times. Topic collections Contact me when new articles are published in these topic areas. Surgery; Surgical Physiology; Surgical Infections; Randomiz...