in this study, the effects of separate and combined intraperitoneal (ip) injections of histidine and dexamethasone were investigated on local inflammation in rats. local inflammation was induced by subcutaneous (sc) injection of histamine (100 μl, 0.1%) in ventral surface of right hind paw. the thickness of paw was measured at 30 min before and 30, 60, 90, 120, 150 and 180 min after injection o...

objective: menopause is the condition when regular menstrual periods cease and may be accompanied by psychological and physical symptoms. the purpose of current study was to determine nigella sativa effects on reproductive system in experimental menopause animal models. materials and methods: a series of experiments wasconducted to investigate the effects of different dosages of n. sativa (firs...

results in all the groups, complete hemostasis occurred. hemostasis times of different concentrations of ferric sulfate were significantly less than those of the control group (p < 0.001). objectives this study attempted to determine the haemostatic effect of ferric sulfate and compare it with the standard method (suturing technique). materials and methods in this animal model study, 60 male wi...

introduction: bacterial translocation is defined as the passage of bacteria from intestinal tract to the extraintestinal organs such as the peritoneum and blood circulation. the aim of this study is to examine bacterial translocation (regarding type of bacteria and effect of time of obstruction on bacterial translocation) from intestinal lumen to the peritoneum and viscera in acute, simple mech...

introduction: cyclophosphamide (cp) is used for the treatment of various cancers. in spite of its therapeutic importance, a wide range of adverse effects such as reproductive toxicity has been observed following the administration of this drug in human and experimental animals. in the current study, we have investigated the adverse effects of cp on morphology and histology of testis rats. metho...

introduction: toxic effects of pesticides are commonly associated with reactive oxygen species damage and pentoxifylline a phosphodiesterase inhibitor is a drug well known for antioxidant properties. the purpose of this study was to evaluate the oxidative damages following a subacute exposure to malathion, an organophosphorus insecticide and pentoxifylline&apos;s ability to counteract these eff...

background: ritalin (methylphenidate methylphenidate) is an amphetamine used to treat adhd, symptoms of narcolepsy, and some people with depression. this study was to investigate the effect of ritalin food on blood albumin and some liver enzymes. materials and methods: in this study, 40 male wistar rats were randomized into 4 groups (1 control group, and three experimental groups). in the contr...

purpose previous studies have shown that physical activity improves learning and memory. present study was performed to determine the effects of short term and long term treadmill exercise on learning, memory consolidation and retrieval of passive avoidance learning in an animal model. methods in this study fifty male wistar rats with 3-4 months of age were randomly divided into five groups (n=...

conclusions: saffron, as an antioxidant, is positively effective on sperm parameters in rats exposed with cadmium. objectives: the aim of this study was to determine the effects of saffron on the results of semen parameters (sperm concentration, motility and viability in cauda of epididymis) in rats exposed to cadmium. materials and methods: thirty wistar male rats were divided into four groups...

objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (otm) in rats. materials and methods: forty male 250-300 g sprague-dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. orthodontic appliances were ligated between the maxillary first molars and in...