Imaging modalities including magnetic resonance imaging and X-ray computed tomography are established methods in daily clinical diagnosis of human brain. Clinical equipment does not provide sufficient spatial resolution to obtain morphological information on the cellular level, essential for applying minimally or non-invasive surgical interventions. Therefore, generic data with lateral sub-micr...

Cystic lymphangiomas are extremely rare benign vascular neoplasms generally found in childhood. Thought to arise from obstructed lymphatic channels during development, but may also secondary trauma, inflammation, malignancy, and surgery or radiation exposure. They usually seen the head neck axillary region, rarely abdominal cavity with only 1% occurring retroperitoneum. These typically asymptom...

BACKGROUND Image intensifiers have become popular due to the concept of minimally invasive surgeries leading to decreasing invasiveness, decreased operative time, and less morbidity. The drawback, however, is an increased risk of radiation exposure to surgeon, patient and theatre staff. These exposures have been of concern due to their potential ability to produce biological effects. The presen...

Primary lung sarcomas are rare but aggressive tumors accounting for less than 0.5% of all lung tumors. The diagnosis of primary lung sarcoma should only be considered after exclusion of other sites. A 32-year-old female presented with recurrent hemorrhagic pleural effusions, shortness of breath and persistent cough. Pleural effusion was drained twice, and each time its analysis was normal. Pati...

Abstract While atom probe tomography (APT) offers 3D spatially-resolved compositional characterization at the nanometer scale, individual inspection of large datasets is time demanding and interpretation thereof highly operator-dependent. Recently, decomposition behavior (V,Al)N thin films was investigated by APT. The conventional analysis, employing standard tools from commercial software, lab...

The “digits” small-vocabulary task is important for many telephone-based applications such as computer-assisted long-distance dialing or credit-card billing, requires extremely high accuracy, and focuses research on acoustic-level processing. On the other hand, in many other tasks a speaker-independent domain-specific vocabulary (such as “collect call”, “calling card”, “operator”, or “help”) ne...

BACKGROUND Cryptococcus neoformans is an encapsulated yeast. There is still little quick and effective solution for the diagnosis or treatment of C. neoformans infection at an early stage in clinical. Antibody-conjugated silica-modified gold nanorods (GNR-SiO2-Ab) can conjugate C. neoformans selectively. It may provide a possibility for treatment of cryptococcosis safely and effectively. METH...

This paper introduces Sentient Sketchbook, a tool which supports a designer in the creation of game levels. Using map sketches to alleviate designer effort, the tool automates playability checks and evaluations and visualizes significant gameplay properties. Most importantly, this paper introduces constrained novelty search via a two-population paradigm for generating, in real-time, alternative...

The design and testing of LED lamps are vital steps toward broader use of LED lighting for outdoor illumination and traffic signalling. The characteristics of LED sources, in combination with the need to limit light pollution and power consumption, require a precise optical design. In particular, in every step of the process, it is important to closely compare theoretical or simulated results w...

This paper describes a system of computer-aided diagnosis using an English Electric KDF9 computer linked to a terminal in a busy clinical department. Data from a series of patients were recorded, coded, and entered into the computer, which then performed a Bayesian analysis and displayed diagnostic probabilities in an adaptable format. Experience in this setting suggests that computer diagnosis...