Pro-inflammatory cytokines play a vital role in periodontitis, obesity and chronic diseases. Retinol binding protein 4 (RBP4), novel adipokine has been implicated as pro-inflammatory marker other systemic In periodontal disease, RBP4 correlated with markers of low-grade inflammation. can directly induce the production mediators involved leukocyte recruitment adherence, including vascular cell a...

Background As an endocrine organ, adipose tissue produces and secretes lots of hormones and adipokines that play important roles in metabolism and inflammation [1]. Varied adipose tissues may affect the inflammation distinctively, mainly because of the different secretion levels of the adipokines. Adipokines like visfatin and retinol binding protein-4 (RBP4) may have important roles in insulin ...

BACKGROUND Retinol-binding protein 4 (RBP4) is an adipokine identified as a marker of insulin resistance in mice and humans. Protein tyrosine phosphatase 1B (PTP1B) expression levels as well as other genes involved in the endoplasmic reticulum (ER) stress response are increased in adipose tissue of obese, high-fat-diet-fed mice. In this study we investigated if serum and/or adipose tissue RBP4 ...

Background and Aims. The secretion of several adipocytokines, such as adiponectin, retinol-binding protein 4 (RBP4), adipocyte fatty acid binding protein (aFABP), and visfatin, is altered in subjects with abdominal adiposity; these endocrine alterations could contribute to increased cardiovascular risk. The aim of the study was to assess the relationship among adiponectin, RBP4, aFABP, and visf...

results rbp4 levels in obese children (19 482.9 ± 3 302.2 pg/ml) were higher than those found in the lean control group (14 295.68 ± 2 381.3 pg/ml) (p < 0.05). in the obese patients, rbp4 levels showed a significant correlation with the grade of fatty liver and bmi (p < 0.05). conclusions it was found that the level of rbp4 had a strong correlation with the severity of fatty liver. therefore, r...

Background & Objective: Diabetic retinopathy (DR) is a common microvascular complication of type 2 diabetes mellitus (T2DM) and the leading cause of vision loss in working-age adults. Vitamin A (retinol) has a role in the mechanism of vision process and retinol binding protein-4 (RBP4), is a carrier of vitamin A, and as an adipokine may be associated with increased risk for insulin resistance a...

Background & Aims: Retinol-binding protein 4 (RBP4) as an adipokine is involved in regulating insulin function and glucose metabolism. Serum levels of RBP4 have been identified as one of the most effective factors in impaired glucose tolerance and diabetes. Studies have shown that exercise improves metabolic syndrome and hepatotoxicity. But the effects of Aqua training on liver Enzymes in diabe...

Moghadasi, M.; Nuri, R.; Ahmadi, N. Effects of 8 weeks high intensity aerobic exercise on serum retinol binding protein 4 levels in female athletes. Brazilian Journal of Biomotricity. v. 7, n. 1, p. 37-42, 2013. Retinol binding protein 4 (RBP4), has recently been identified as novel adipokines associated with obesity, type 2 diabetes and the metabolic syndrome. The effects of exercise training ...