APPROXIMATELY 10,000 autologous hematopoietic stem cell (HSC) transplants are performed worldwide each year for malignant diseases.1 Results of randomized trials in recent years suggest that high-dose chemotherapy followed by infusion of autologous HSCs can offer prolonged disease-free survival in hematologic malignancies including non-Hodgkin’s lymphoma in relapse,2 acute myelogenous leukemia,...

One of the major challenges of allogeneic stem cell transplantation (allo-SCT) is to reduce the risk of graft-versus-host disease (GVHD) while boosting the graft-versus-leukemia (GVL) effect. The reconstitution of natural killer (NK) cells following allo-SCT is of notable interest due to their known capability to induce GVL without GVHD. Here, in this study, we investigate the association betwe...

Background. HIV-positive people starting combined antiretroviral therapy may develop immune reconstitution to latent or treated opportunistic infections. Immune reconstitution to cerebral Cryptococcus is poorly understood and can be fatal. Case Presentation. A 33-year-old Zimbabwean female presented with cryptococcal meningitis and newly diagnosed HIV with a CD4 count of 51 cells/ μ L (4%). She...

The mechanisms by which reconstitution increases rumen degradation of grain sorghum and relevant studies that have measured effects of reconstitution on growth performance by finishing cattle were reviewed. The growth performance data summarized indicate that reconstitution of sorghum improved feed efficiency by 15% when compared to dry-rolled sorghum with a 7.6% increase in rate of gain. Indiv...

The cause of hairy cell leukemia (HCL) is unknown. Current treatments seem effective only for a limited period of time. In addition, a significant proportion of patients remain refractive to all treatment options. These considerations indicate the need to develop alternative therapeutic strategies for HCL. Here, we report that HCL is characterized by underexpression of RhoH. In vitro reconstitu...

Reconstitution is the process of mixing solvent medium into a dry powder mass to produce suspended or dissolved substances. Mixing injection drugs, including reconstitution antibiotic injections, should be formulated by pharmacists, in fact all them are still made non-pharmaceutical health workers, apart from lack correlation, it also gives impression that hospital violating rules. To prevent e...

Filaments from isolated flagella of Caulobacter crescentus have been purified by successive dissociation and reconstitution. After the second and third reconstitutions from subunits in 0.8 M sodium citrate, filament preparations contained only two proteins, flagellin A (26,000 daltons) and flagellin B (28,000 daltons). There was some enrichment for flagellin A during reconstitution by this proc...