The dominant outward rectifier K+ currents were examined in protoplasts from Vicia faba guard cells. In whole-cell patch-clamp recordings, we generally observed that the conductance of the K+ inward and the outward rectifier gradually decreases. As a consequence of this run down a new steady state was achieved which was 90 ± 5% lower than that obtained at the beginning of the recording. The run...

Potassium currents are an important factor in repolarizing the membrane potential and determining the level of neuronal excitability. We compared potassium currents in CA1 hippocampal neurons dissociated from young (2-3 months old) and old (26-30 months old) Sprague-Dawley rats. Whole-cell patch-clamp techniques were used to measure the delayed rectifier (sustained) and the A-type (transient) p...

This paper describes a completely digitally controlled high-performance low-harmonic rectifier. It is shown that the dynamics of the outer voltage loop can be significantly improved using a self-tuning digital comb filter. Low input current harmonics and fast voltage transient responses are experimentally verified on a 200W universal-input boost rectifier operating at the switching frequency of...

This paper provides a theoretical justification of the superior classification performance of deep rectifier networks over shallow rectifier networks from the geometrical perspective of piecewise linear (PWL) classifier boundaries. We show that, for a given threshold on the approximation error, the required number of boundary facets to approximate a general smooth boundary grows exponentially w...

OBJECTIVES This study evaluated the in vivo electrophysiological effects of a highly selective slow delayed-rectifier K+-current blocker, HMR 1556, to gain insights into the consequences of selectively inhibiting the slow delayed-rectifier current in vivo. METHODS Atrial and ventricular effective refractory periods, sinus node recovery time, Wenckebach cycle-length, atrial fibrillation durati...