Maintenance of a negative membrane potential in the cortical collecting duct (CCD) principal cell depends on a small-conductance, inward-rectifying basolateral membrane K+(Kir) channel. In the present study, a candidate cDNA encoding this K+ channel, CCD-IRK3, was isolated from a mouse collecting duct cell line, M1. CCD-IRK3 shares a high degree of homology with a human brain inward-rectifier K...

this paper describes optimization method that combines the plackett-burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of l-asparaginase by serratia marcescens sb08. four medium factors, from out of 11 medium factors, were screened by plackett-burman design experiments and subsequent optimization process to find out the o...

Objectives: To investigate the clinical and pathological characteristics of central core disease (CCD) in China. Methods: A retrospective analysis was performed on the clinical data of 40 patients with CCD who presented at our department or other hospitals from 1986 to 2013. Muscle histochemical staining was used to study the muscular pathological characteristics of patients with CCD. Results: ...

In a service environment a service provider needs to determine the amount and kinds of capacity to meet customers’ needs over many periods. To make good decisions, she needs to know the probability distribution of her customers’ demand in each period. We study a situation in which customers’ demand for a given service is random in each period, but inelastic, or modeled well by this assumption, ...

Real-time inspections for the large-scale solar system may take a long time to get hazard situations any failures that place in panels normal operations, where prior hazards detection is important. Reducing execution and improving system’s performance are ultimate goals of multiprocessing or multicore systems. video processing analysis from two camcorders, thermal charge-coupling devices (CCD),...

CMOS image sensors are today challenging the existing Charge Coupled Devices (CCD) in several application fields. Improved architecture and processes have to a large extent overcome early weaknesses of CMOS imagers, namely with respect to noise and sensitivity. Todays " Active Pixel Sensors" are typically based on sub-micron technologies that have been optimized for optical sensing and can riva...

Crossed cerebellar diaschisis (CCD) is well described in the chronic phase of stroke, but few data describe acute CCD and its serial changes after reperfusion. Using positron emission tomography (PET), we studied acute CCD with respect to supratentorial perfusion and outcome measures. In 19 acute stroke patients receiving intravenous thrombolysis (<3 h), 15O-water PET assessed CCD and supratent...

Modern X-ray imaging systems evolve toward digitization for reduced cost, faster time-to-diagnosis, and improved diagnostic confidence. For the digital X-ray systems, charge coupled device (CCD) technology is commonly used to detect and digitize optical X-ray image. This paper presents a novel soft-test/repair approach to overcome the defective pixel problem in CCD-based digital X-ray systems t...

INTRODUCTION Cleidocranial Dysplasia (CCD) is a rare inherited autosomal dominant congenital syndrome that occurs in approximately one out of every one million individuals worldwide; it primarily affects bones that undergo intra-membranous ossification, generally the skull and clavicles. Other bones may be affected such as the long bones, spine, pelvis, bones of hands and feet showing hypoplasi...