We consider a two echelon supply chain with a single retailer and a single manufacturer. Inventory replenishment policies at the retailer level transmit customer demand variability to the manufacturer, sometimes even in an amplified form (known as the bullwhip effect). When production is inflexible at the manufacturing level, significant costs may be incurred by ramping up and down production l...

Pharmaceutical and specialty chemical production often causes high waste to product ratios. This can be explained by complex reaction mechanisms that require complicated multi-step production routes as well as stringent product purity and quality requirements. Therefore a large number of different types and levels of waste are leaving pharmaceutical production campaigns and need material recove...

In this paper, we revisit an important issue of CDCL-based SAT solvers, namely the learned clauses database management policies. Our motivation takes its source from a simple observation on the remarkable performances of both random and size-bounded reduction strategies. We first derive a simple reduction strategy, called Size-Bounded Randomized strategy (in short SBR), that combines maintaing ...

Niche dependent differential gene loss and overlapping genes have been proposed as means of achieving genome reduction by retaining indispensable genes and compressing maximum amount of information in available sequence space. Herein, we analyzed the differential gene loss and overlapping genes in bacterial genomes with different lifestyles. Our results clearly suggest that gene loss and overla...

We develop strategies for integrated use of certain well-known variance reduction techniques to estimate a mean response in a finite-horizon simulation experiment. The building blocks for these integrated variance reduction strategies are the techniques of conditional expectation, correlation induction (including antithetic variates and Latin hypercube sampling), and control variates; and all p...

This Trends and Issues on fear of crime, and its reduction in Australia, represents an outstanding illustration of the contribution which criminological research can make to public policy. Various surveys in recent years have identified a number of factors consistently associated with fear of crime. These are gender (females tend to be more fearful than males) and the presence of disorder and i...

All correctional services face the challenge of ‘doing more with less’. Doing more means that they are expected not only to ‘house’ prisoners in a safe and secure environment but also to deliver rehabilitative programmes and to prepare prisoners for release. Importantly, they must also meet the growing expectations of external accountability agencies including human rights organizations. Doing ...

We present work on the task of reducing noise in nominal terminology extraction. Based on a comparative evaluation of statistical measures aimed at capturing domain specificity, we propose strategies to increase the typically quite low accuracy of classical hybrid nominal multi-word term extraction. Our experiments on a set of German do-it-yourself instruction texts show that using linguistic f...

Risks permeate the development and operation of many complex software systems. Nearly all risk reduction activities incur cost, and the sum total cost of all potentially applicable activities typically far exceeds the resources available. Hence there is the need to judiciously pick from among those activities to arrive at a costeffective selection. We call the approach to make this selection a ...