We investigate incorporating structural information from segmentation into a groupwise registration framework. Previous work by Petrovic et al., using MR brain images, showed that using tissue fractions to help construct an intensity reference image gives better results than just using intensity images alone. In their work, a Gaussian Mixture Model (GMM) was fitted to the 1D intensity histogram...

Background: In this study, Quantitative 32P bremsstrahlung planar and SPECT imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate Dosimetry in clinical practice. Materials and Methods: CT, planar and SPECT bremsstrahlung images of Jaszczak phantom containing a known activity of 32P were acquired. In addition, Phanto...

Pedicle screw placement for vertebral fixation is a complicated surgery orthopaedic surgeons. The main challenge to estimate the accurate trajectory’s position minimize post-operative complications related pedicle placement. Different types of 3D 2D registration techniques have been employed avoid misplacement during surgery. However, these cannot be applied directly MR X-ray due differences in...

BACKGROUND AND PURPOSE Clinical brain MR imaging registration algorithms are often made available by commercial vendors without figures of merit. The purpose of this study was to suggest a rational performance comparison methodology for these products. MATERIALS AND METHODS Twenty patients were imaged on clinical 3T scanners by using 4 sequences: T2-weighted, FLAIR, susceptibility-weighted an...

Evidence regarding the effectiveness of health technologies can be distorted via numerous mechanisms, including publication bias, methodological errors, over-interpretation of findings and fraud. In recent years, popular science writers have brought these issues to the fore, resulting in popular movements to improve the credibility of science. One particularly effective campaign has been that o...

In response to government initiatives and the rise in patient empowerment, nurses are increasingly being challenged to deliver high-quality care supported by evidence-based practice. This can be a challenge for nurse educators providing the foundation for pre-registration student nurses. Evidence-based practice within nursing is achieved by developing and supporting patient-centred approaches t...