The sensitivity of radiographic diagnosis of silicosis in an occupational medical care (primary examination) varied between 39% and 71%, and the specifity between 60% and 99%. This means that, if the prevalence of silicosis in dust exposed population is between 2% and 8%, 23% to 56% of silicosis cases are likely to be falsely diagnosed. The dependence of misdiagnosis of silicosis on the prevale...

Duplications in 16p11.2 are a risk factor for schizophrenia (SCZ). Using genetically modified zebrafish, Golzio and colleagues identified KCTD13 within 16p11.2 as a major driver of the neuropsychiatric phenotype observed in humans. The aims of the present study were to explore the role of KCTD13 in the development of SCZ and to provide a more complete picture of the allelic architecture at this...

Insufficient performance of cleaning and disinfection of flexible endoscopes can pose an infection risk to patients. Actually quality of reprocessing is checked by performing microbiological cultures. Unfortunately, their results are not available on the same day so that more rapid methods are desirable. We compared the ATP (adenosine triphosphate) bioluminescence for hygiene checking of the re...

Transmission electron microscopy has become a major characterisation tool with an ever increasing variety of methods being applied in wide range scientific fields. However, the probably most famous pitfall related workflows is preparation high-quality electron-transparent lamellae enabling for extraction valuable and reliable information. Particularly field solid state physics materials science...

Allometry, in general biology, measures the relative growth of a part in relation to the whole living organism. Left ventricular hypertrophy (LVH) is the heart adaptation to excessive load (systolic or diastolic). The increase in left ventricular mass leads to an increase in the electrocardiographic voltages. Based on clinical data, we compared the allometric behavior of three different ECG mar...