in this study, attempts were made to evaluate the effect of various acrylic acid based carbopols on the release profile of a beta-adrenoreceptor blocking drug, propranolol hcl, from matrix-type tablets invitro. for this purpose, tablets containing 160 mg of propranolol hcl along with various amounts of carbopols 934 (c934), 971 (c971), 974 (c974) and pemulen (pem) were prepared using the wet gr...

The extent of piracy for a specific digital good can be characterized by the laws of demand and supply. The music industry and its trade organization, the RIAA, have recognized this and taken aggressive steps to diminish demand as well as supply. In this study, we develop a model that describes the dynamics of demand and supply-side of piracy propagation. Using the model, we investigate the eff...

date bunch fading (dbf) is a serious disease of date palm (phoenix dactelifera l.) in iran. fusarium proliferatum was isolated from the xylem of fruit bunch samples sent from kerman and fars provinces groves to the laboratory. koch’s postulates were completed in the greenhouse by crown injection and root inoculations. shriveling of the fruits was induced by peduncle inoculations. symptoms on th...

Breeding at the right time is important for successful reproduction. In birds, stressful environmental conditions are known to delay the timing of breeding but the underlying mechanisms are poorly understood. The stress hormone corticosterone appears to be a good candidate for mediating egg-laying date according to early environmental conditions and physiological state. By experimentally reduci...

We study the following energy-efficient scheduling problem. We are given a set of n jobs which have to be scheduled by a single processor whose speed can be varied dynamically. Each job Jj is characterized by a processing requirement (work) pj , a release date rj and a deadline dj . We are also given a budget of energy E which must not be exceeded and our objective is to maximize the throughput...

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...

Draft agreed by Efficacy Working Party June 2007 Adopted by CHMP for release for consultation 19 July 2007 End of consultation (deadline for comments) 31 January 2008 Agreed by Efficacy Working Party July 2008 Adopted by CHMP 24 July 2008 Date for coming into effect 1 February 2009 Updated draft agreed by CNS Working Party June 2012 Adopted by CHMP 21 June 2012 Start of public consultation n/a ...