Our motivation is the notion of \timed-release crypto," where the goal is to encrypt a message so that it can not be decrypted by anyone, not even the sender, until a pre-determined amount of time has passed. The goal is to \send information into the future." This problem was rst discussed by Timothy May [6]. What are the applications of \timed-release crypto"? Here are a few possibilities (som...

objective(s): in a new approach, following the development in metal oxide chemistry, the ibuprofen as low water soluble nonsteroidal anti-inflammatory drug diffused into synthetic sol-gel derived nano porous g-alumina by an impregnation method in order to increase the solubility and control the drug release in physiological environment. methods: sol-gel method was utilized for the fabrication o...

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...

objective(s): ketotifen fumarate (kf) is a selective and noncompetitive histamine antagonist (h1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. the aim of this study was to formulate and improve an ophthalmic delivery system of kf.ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...

the objective of the present study was to design an oral controlled drug delivery system for sparingly soluble diclofenac sodium (dcl) using guar gum as triple-layer matrix tablets. matrix tablet granules containing 30% (d1), 40% (d2) or 50% (d3) of guar gum were prepared by the conventional wet granulation technique. matrix tablets of diclofenac sodium were prepared by compressing three layers...

      Extended release formulation of alfuzosin, an a-antagonist used for prostatic hypertrophy, is available in market. It is convenient for older patients to take only one tablet a day. Marketed alfuzosin formulation is three layered geomatrix tablet that requires special facilities, high cost, more time and complex operation than normal direct compression formulation. Therefore, a less compl...

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