Anaplastic glioma is Grade III and the median overall survival is about 37.6 months. However, there are still other factors that affect the prognosis for anaplastic glioma patients due to variable overall survival. So we screened four-lncRNA signature (AGAP2-AS1, TPT1-AS1, LINC01198 and MIR155HG) from the lncRNA expression profile from the GSE16011, CGGA and REMBRANDT datasets. The patients in ...

background successful pregnancy is the ultimate goal of almost all couples. however, this pleasant event is usually accompanied psychological and behavioral changes and can result in stress in women, particularly women who pregnant by assisted reproductive technology methods (arts). objectives this study aims to determine the anxiety level during pregnancy and its relation with infertility fact...

Introduction: Paintings are versatile near-planar objects with material characteristics that vary widely. The fact that paint has a material presence is often overlooked, mostly due to the fact that we encounter many of these artworks through two dimensional reproductions. The capture of paintings in the third dimension is not only interesting for study, restoration and conservation, but it als...

Glioma is the most malignant brain tumor and glioblastoma (GBM) is the most aggressive type. The involvement of N-myc (and STAT) interactor (NMI) in tumorigenesis was sporadically reported but far from elucidation. This study aims to investigate roles of NMI in human glioma. Three independent cohorts, the Chinese tissue microarray (TMA) cohort (N = 209), the Repository for Molecular Brain Neopl...

BACKGROUND Glioblastoma can be classified into four distinct molecular subtypes (Proneural, Neural, Classical and Mesenchymal), based on gene expression profiling. This study aimed to investigate the prevalence, clinicopathologic features and overall survival (OS) of the four molecular subtypes among all malignant gliomas. METHODS A total of 941 gene expression arrays with clinical data were ...

Eckhard Hess claimed that pupils dilate to pleasant images and constrict to unpleasant images. However, his work was confounded since his image's luminances and contrasts across conditions were inconsistent. We overcome this limitation and suggest a new, promising methodology for research in this area. We presented rightward or leftward facing male and female portraits by Rembrandt to observers...

Poor prognosis of glioblastoma multiforme is strongly associated with the ability of tumor cells to invade the brain parenchyma, which is believed to be the major factor responsible for glioblastoma recurrence. Therefore, identifying the molecular mechanisms driving invasion may lead to the development of improved therapies for glioblastoma patients. Here, we investigated the role of procollage...

intrathecal administration of midazolam has been reported to have antinociceptive action, and to be an effective analgesic agent. in this prospective double-blind study we aimed to evaluate the postoperative effects of intrathecal midazolam with lidocaine following perineal operation. forty patients were randomly allocated to two groups: 20 patients in the control group received 2 ml of 5% heav...

objective: the aim of this study was to assess skeletal relapse in patients who underwent mandibular setback by bilateral sagittal split ramus osteotomy (bssro) and osteosynthesis wiring techniques. materials and methods: in this semi-experimental study, 10 patients (8 women, 2 men) with 3-8 millimeters overjet underwent mandibular setback with bssro, osteosynthesis wiring and inter maxillary f...

background: knowledge of infertile couples about assisted reproductive technology is a fundamental parameter to optimize the infertility treatment and conduct it cooperatively. objective: to evaluate knowledge and attitude of infertile couples about assisted reproductive technology we designed a descriptive cross-sectional study. materials and methods: 400 infertile patients were investigated b...