BACKGROUND AND PURPOSE Poststroke cognitive impairment occurs frequently in young patients with ischemic stroke (18 through 50 years of age). Accumulating data suggest that stroke is associated with lower white matter integrity remote from the stroke impact area, which might explain why some patients have good long-term cognitive outcome and others do not. Given the life expectancy of decades i...

Background: Paraplegia is a major devastating and unpredictable complication of spinal cord ischemic reperfusion injury (SC-IRI). Ischemic preconditioning (IPC) is a procedure whereby a brief episode of non-lethal ischemia to an organ produces protection against subsequent detrimental ischemic-reperfusion insult to that organ. It has been shown that IPC may not only induce a local protective ef...

Introduction: Ischemic preconditioning (IPC) protects skeletal muscles from ischemia-reperfusion injury and improves physical exercise performance. The purpose of the present study was to determine whether application of remote ischemic preconditioning (RIPC) of upper limbs would affect the pulmonary function tests and the maximal oxygen consumption (VO2max). Methods: Twenty healthy trained...

BACKGROUND Outcomes after acute myocardial infarction in patients with chronic kidney disease are extremely poor. Ischemic conditioning techniques are among the most powerful cytoprotective strategies discovered to date. However, experimental data suggest that comorbidity may attenuate the protective effects of ischemic conditioning. METHODS AND RESULTS We conducted investigations into the ef...

Background—Outcomes after acute myocardial infarction in patients with chronic kidney disease are extremely poor. Ischemic conditioning techniques are among the most powerful cytoprotective strategies discovered to date. However, experimental data suggest that comorbidity may attenuate the protective effects of ischemic conditioning. Methods and Results—We conducted investigations into the effe...