نتایج جستجو برای: reperfusion injury mesenchymal stem cells rats

تعداد نتایج: 2000041  

Journal: :Advanced Healthcare Materials 2023

Mesenchymal Stem Cell-Hybrid Nanovehicles In article 2300376, Donghang Xu, Tianyuan Zhang, Jianqing Gao and co-workers develop a biomimetic nanovehicle hybridizing the cell membrane of mesenchymal stem with liposome. This hybrid shows advantages both highly efficient inflammation targeting good drug-loading capacity, resulting in specifically targeted delivery methylprednisolone to inflammatory...

Journal: :iranian journal of allergy, asthma and immunology 0
razieh alipour department of immunology, medical school, isfahan university of medical sciences, isfahan, iran minoo adib department of immunology, medical school, isfahan university of medical sciences, isfahan, iran masoumeh masoumi karimi department of immunology, medical school, isfahan university of medical sciences, isfahan, iran batool hashemi-beni department of anatomical sciences and molecular biology, medical school, isfahan university of medical sciences, isfahan, iran nasrin sereshki department of immunology, medical school, isfahan university of medical sciences, isfahan, iran

stem cells from human exfoliated deciduous teeth (shed) have been introduced recently and  possess characteristics similar to  mesenchymal stem  cells (mscs). because of  their convenient accessibility and safety of harvest, shed can be a preferable source for the ever- increasing mscs’ applications. while they are new, their immunoproperties have not been adequately studied. in this study, we ...

2014
Zhiyuan Li Zhanxiu Zhang Lili Zhao Hui Li Suxia Wang Yong Shen

We hypothesized that RNA interference to silence Nogo-66 receptor gene expression in bone marrow mesenchymal stem cells before transplantation might further improve neurological function in rats with spinal cord transection injury. After 2 weeks, the number of neurons and BrdU-positive cells in the Nogo-66 receptor gene silencing group was higher than in the bone marrow mesenchymal stem cell gr...

2009
Patricia Semedo Matheus Corrêa-Costa Marcos Antonio Cenedeze Maria Heloisa Massola Shimizu Antonio Carlos Seguro Alvaro Pacheco-Silva Niels Olsen Saraiva Câmara

Objective: To investigate the role of mesenchymal stem cells in fibrogenesis using a model of chronic renal insufficiency. Methods: Mesenchymal stem cells were obtained from tibias and femurs of Wistar-EPM rats. After three to five passages, the cells were submitted to phenotypic analyses and differentiation. Wistar rats were submitted to the 5/6 nephrectomy model, and 2.105 mesenchymal stem ce...

Journal: :Indian Journal of Pharmaceutical Sciences 2021

To investigate the expression of autophagy markers brain cells and effect propofol on during myocardial ischemia-reperfusion in type 2 diabetic rats. 36 healthy male Sprague Dawley rats were randomly divided into 6 groups, each group, fed with high-sugar high-fat diet for 8 w intraperitoneal injection streptozotocin to prepare rat model diabetes. The groups are: sham operation ischemia reperfus...

Journal: :nanomedicine journal 0
a. doustgani department of chemical engineering, university of zanjan, zanjan, iranسازمان اصلی تایید شده: دانشگاه زنجان (zanjan university) m. s. pedram faculty of veterinary medicine, university of tehran, tehran, iranسازمان اصلی تایید شده: دانشگاه تهران (tehran university)

objective(s): in this study, the effect of electrospun fiber orientation on proliferation and differentiation of mesenchymal stem cells (mscs) was evaluated. materials and methods: aligned and random nanocomposite nanofibrous scaffolds were electrospun from polylactic acid (pla), poly (vinyl alcohol) (pva) and calcium carbonate nanoparticles (ncap). the surface morphology of prepared nanofibrou...

Journal: :anatomical sciences journal 0
narges talebian kazem parivar laya kafami mohsen marzban maryam shirmohammadi mohammad taghi joghataei

introduction: bone marrow (bm) is a known source of mesenchymal stem cells (mscs) that are used for cell therapy. this study attempts to identify if the wharton’s jelly (wj) is a suitable substitute for bm as a source for mscs. materials and methods: a population of human wj and bm stem cells were isolated and incubated with fluorescein conjugated antibodies for five specific msc markers. cell ...

Journal: :cell journal 0
karim shams mahshid saleh aliakbar movassaghpour parvin akbarzadeh zahra molaeipour

objective: bone marrow mesenchymal stem cells reside in bone marrow and support homing and differentiation of hematopoietic stem cells (1). this makes them an excellent instrument for regenerative treatment and co-culture with the hsc. materials and methods: in this study, k562 cell lines were treated with butyric acid(for erythroid differentiation), co-cultured with mesenchymal stem cells and ...

Journal: :nephro-urology monthly 0
heihachi migita department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan; department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan. tel: +81-982235555, fax: +81-9825618 shigenori yoshitake department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan yoshihiro tange department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan narantsog choijookhuu department of anatomy, faculty of medicine, division of histochemistry and cell biology, university of miyazaki, kyotake, miyazaki, japan yoshitaka hishikawa department of anatomy, faculty of medicine, division of histochemistry and cell biology, university of miyazaki, kyotake, miyazaki, japan

results a significant decrease in apoptotic cells and increase in proliferative reaction were observed in the i/r + hbo group compared to the i/r group. conclusions we demonstrated that hbo suppressed apoptosis, which caused inflammation after renal i/r, and promoted tubular cell regeneration. hbo has protective effects against aki caused by renal i/r through the inhibition of apoptosis. materi...

2013
Irina A. Potapova Ira S. Cohen Sergey V. Doronin

Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood. We have shown that the development of apoptosis in endothelial cells stimulates endothelial cell adhesiveness for mesenchymal stem cells. Adhesion of mesenchymal stem cells to apoptotic endothelial cells de...

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