نتایج جستجو برای: reperfusion injury mesenchymal stem cells rats

تعداد نتایج: 2000041  

Arash Abdi, Behjat Seifi, Fariba Akhondzadeh, Farzaneh Kianian, Kamal Abdolmohammadi, Mehri Kadkhodaee, Mina Ranjbaran,

Background: In the present study, we hypothesized that conditioned medium (CM) derived from mesenchymal stem cells attenuates the brain oxidative stress in sepsis induced by the cecal ligation and puncture (CLP) model. Methods: This study was performed in the Department of Physiology at Tehran University of Medical Sciences from August 2018 to April 2019. Conditioned medium was collected from ...

Journal: :international journal of hematology-oncology and stem cell research 0
naser mobarra department of clinical biochemistry, school of medicine, tehran university of medical sciences, tehran, iran ; students'sciences research center, tehran university of medical sciences, tehran, iran. masoud soleimani department of hematology, school of medical sciences, tarbiat modares university, tehran, iran. fatemeh kouhkan department of molecular biology and genetic engineering, stem cell technology research center, tehran, iran. zahra hesari department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran. reyhaneh lahmy department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran. majid mossahebi-mohammadi department of hematology, school of medical sciences, tarbiat modares university, tehran, iran.

background: the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. differentiation of human induced pluripotent stem cells (hipscs) to hepatocyte-like cells (hlcs) on mouse embryonic fibroblasts (mefs) feeders is confronted with several problems that hinder the clinical applications of these differentiated cells for the treatment of liver injuries. ...

Journal: :Food Science and Technology 2021

MicroR-146 (miR-146) plays crucial roles in attenuating nerve injury during cerebral ischemia-reperfusion (I/R) injury. The purpose of this study was to investigate the neuroprotective effect miR-146 against I/R Rat model established using 4-vessel occlusion and reperfusion. In study, expression significantly decreased neurons rat compared sham group. addition, miR-146+/+ inflammatory cytokines...

Journal: :international journal of reproductive biomedicine 0
maryam hosseinzadeh shirzeily parichehr pasbakhsh fardin amidi kobra mehrannia

background: recent publications about differentiation of stem cells to germ cells have motivated researchers to make new approaches to infertility. in vitro production of germ cells improves understanding differentiation process of male and female germ cells. due to the problem of using embryonic stem cells (esc), it’s necessary the mentioned cells be replaced with some adult multi-potent stem ...

Journal: :Small 2021

Despite the latest advances in cardiovascular biology and medicine, myocardial infarction (MI) remains one of major causes deaths worldwide. While reperfusion myocardium is critical to limit ischemic damage typical a MI event, it detrimental morphological functional changes known as “reperfusion injury.” This complex scenario poorly represented currently available models ischemia/reperfusion in...

ژورنال: پیاورد سلامت 2015
شهیدی دلشاد, الهام, صابریان, مصطفی, صمدی کوچکسرائی, علی, ناجی, طاهره,

Background and Aim: The use of probiotics has been surveyed in different studies. For example, many researches have been conducted on immunity, cancer and embryonic cells proliferation. Mesenchymal stem cells (MSCs) have a rather slower growth and a more limited number of passages. In this research, the effect of supernatant of Lactobacillus acidophilus (LS) as one of the most commonly used pro...

ژورنال: کومش 2019

Introduction: Degenerative retinal diseases are main cause of irreversible blindness. Stem cells therapy is a promising way in these diseases. Therefore, mesenchymal stem cells because of its safety can produce degenerated cells and can play important role in treatment. The aim of this study was to examine morphological changes in injured retinal pigment epithelium (RPE) and photoreceptor cells...

Journal: :iranian journal of basic medical sciences 0
farshad homayouni moghadam neurobiomedical research center, shahid sadoughi university of medical sciences, yazd, iran 2 department of physiology, school of medicine, shahid sadoughi university of medical sciences, yazd, iran behzad vakili zarch neurobiomedical research center, shahid sadoughi university of medical sciences, yazd, iran mohammad shafiei neurobiomedical research center, shahid sadoughi university of medical sciences, yazd, iran

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Journal: :iranian journal of basic medical sciences 0
mohamadreza baghaban eslaminejad stem cell department, cell sciences research center, royan institute, acecr, tehran, iran. mahmood talkhabi school of biology, college of science, university of tehran, tehran, iran bahman zeynali school of biology, college of science, university of tehran, tehran, iran

objective(s) it is believed that the mesenchymal stem cell (msc) differentiation and proliferation are the results of activation of wnt signaling pathway. on the other hand, lithium chloride is reported to be able to activate this pathway. the objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived msc. materials and ...

Journal: :journal of paramedical sciences 0
faeze pournaqi department of biology, faculty of science, islamic azad university of tehran east, tehran, iran mahnaz farahmand department of biology, faculty of science, islamic azad university of tehran east, tehran, iran abdolreza ardeshirylajimi department of stem cell biology, stem cell technology research center, tehran, iran

today’s tissue engineering is an important and interested method to treatment of  bone lesions so tissue engineering specialists and orthopedic surgeons are forced to serve as a safe alternative to current methods.the introduction ofa scaffoldthathas thebestefficiencyisamajor challengeto scientistsand researchersin this field.the aim ofthisstudy is to investigatethe polyaniline(pani) influence ...

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