This investigation examined effects of chronic (>/=2 yr) hormone replacement therapy (HRT), both estrogen replacement therapy (ERT) and estrogen plus progesterone therapy (E+P), on core temperature and skin blood flow responses of postmenopausal women. Twenty-five postmenopausal women [9 not on HRT (NO), 8 on ERT, 8 on E+P] exercised on a cycle ergometer for 1 h at an ambient temperature of 36 ...

background: premature ovarian failure (pof) is a common condition; its incidence is estimated to be as great as 1 in 100 by the age of 40 years. physiologic replacement of ovarian steroid hormones seems rational until the age of normal menopause. temporary return of ovarian function and pregnancy may occur rarely in women with pof. we report a case of pof who conceived during hormone replacemen...

To examine the influence of chronic hormone replacement therapy (HRT) on the central and peripheral cardiovascular responses of postmenopausal women to direct passive heating, seven women taking estrogen replacement therapy, seven women taking estrogen and progesterone therapy, and seven women not taking HRT were passively heated with water-perfused suits to their individual limit of thermal to...

BACKGROUND For decades, hormone replacement therapy (HRT), which includes both estrogen and progestin, has been administered to postmenopausal women to mainly treat the symptoms of menopause and help prevent osteoporosis, with the added benefit of preventing coronary heart disease (CHD). Recently released study results have left clinicians wondering if HRT should be used at all, and, if so, wit...

The menopause is understood like a menstruation cease, because of sudden fall in hormone production. Generally, the symptoms at this stage are heat waves, lack of vaginal lubrication, loss of skin elasticity, hormonal changes, intensification of bone decalcification and reduction of libido. In order to alleviate these symptoms there are Hormone Replacement Therapies (HRT) that use synthetic dru...

INTRODUCTION In the postmenopausal period, an average of 25% of women will present symptomatic ovarian failure requiring hormonal replacement therapy. Estrogen can relieve vasomotor symptoms. Hormonal replacement therapy is generally not recommended for breast cancer patients due to the potential risk of tumor recurrence. To answer the questions about the safety of hormonal replacement therapy ...

This work was supported by grants from the Medical Research Council, the North of England Cancer Campaign, the Wellcome Trust, the League of Friends of the Royal Victoria Infirmary, the Ernest and Minnie Dawson Cancer Trust, the research committee, Newcastle Area Health Authority (Teaching), and the Welsh Office Scheme for Development of Health and Social Research. We are most grateful to Miss ...

Despite major progress in treatment and prevention, stroke remains the leading cause of disability and the third leading cause of death, surpassed only by heart disease and cancer, in the United States.1 An estimated 500 000 to 600 000 first and 100 000 recurrent strokes occur each year, and '160 000 of these are fatal.2 Among stroke survivors, the burden of long-term disability is great. In th...

Hemophilia A is a bleeding disorder caused by defective production of factor VIII. The main concern associated with the disease is bleeding, especially after trauma and surgeries. Factor VIII replacement therapy is associated with substantial decrease of bleeding events during surgery. However, there have been a number of reports of thromboemblic events in this situ-ation. The present report de...

Partial EN (enteral nutrition) should always be aimed for in patients with renal failure that require nutritional support. Nevertheless PN (parenteral nutrition) may be necessary in renal failure in patient groups with acute or chronic renal failure (ARF or CRF) and additional acute diseases but without extracorporeal renal replacement therapy, or in patients with ARF or CRF with additional acu...