BACKGROUND The presence of residual cervical lesions was evaluated in patients submitted to repeat conization due to a finding of positive endocervical margins in a previous loop electrosurgical excision procedure (LEEP) specimen. In addition, the correlation between the presence of a residual lesion and risk factors for cervical cancer, and the use of repeat conization as first-choice treatmen...

The aim of this study was to determine the incidence rates of HIV1/2 antibodies, HBV and HCV antibodies among voluntary blood donors and to estimate the residual risk of HIV, HBV and HCV infection among blood donors in Bukavu. We conducted a follow-up cohort study of volunteer blood donors who have made at least two blood donations in Bukavu (DRC) between January 2010 and December 2012. We reco...

BACKGROUND Hypertensive individuals on blood pressure (BP)-lowering treatment with BP in the normal or high-normal range have higher cardiovascular risk than untreated persons with usual BP in the same range. This residual risk (relative and absolute) is not well quantified and may be attributable in part to the higher burden of subclinical disease in treated individuals. METHODS AND RESULTS ...

Prevention of cardiovascular disease (CVD) spans the human lifespan, including primordial, primary, and secondary prevention efforts. Extensive evidence from epidemiological, genetic, and animal studies confirms the central importance of elevated low-density lipoprotein (LDL) cholesterol (LDL-C) in atherosclerotic CVD events.1 The Cholesterol Treatment Trialists Collaboration provides perperson...

Until the results of several statin trials are available, it is recommended that the current indications and usage of ezetimibe be continued.

BACKGROUND Despite the molecular heterogeneity of standard-risk acute myeloid leukemia (AML), treatment decisions are based on a limited number of molecular genetic markers and morphology-based assessment of remission. Sensitive detection of a leukemia-specific marker (e.g., a mutation in the gene encoding nucleophosmin [NPM1]) could improve prognostication by identifying submicroscopic disease...

Background and Purpose—Much of our knowledge of risk factors for falls comes from studies of the general population. The aim of this study was to estimate the risk of falling associated with commonly accepted and stroke-specific factors in a home-dwelling stroke population. Methods—This study included an analysis of prospective fall reports in 124 women with confirmed stroke over 1 year. Variab...

Atherosclerotic cardiovascular diseases (CVD) are still the leading cause of morbidity and mortality worldwide, although optimal medical therapy has been prescribed for primary and secondary preventions. Residual cardiovascular risk for some population groups is still considerably high although target low density lipoprotein-cholesterol (LDL-C) level has been achieved. During the past few decad...

Results A total of 505 patients (78% males) with a mean age of 45.6 years (SD 7.6) were enrolled. At baseline the mean CD4 count was 667 cells/μl (SD 268) and VL was < 3 copies/ml in 73.9% and between 3 and 50 copies/ml in the remaining 26.1% of cases. Over the following 8 months period, patients with a baseline VL < 3 copies/ml presented a stable HIV-RNA below this threshold in 72.8% of cases,...

purpose: to evaluate residual refractive errors after cataract surgery and its determinant factors at farabi eye hospital, tehran. methods: simple random sampling was done among cataract surgery scheduled patients over a 4 year period (2003-2006). exclusion criteria were uveitis, previous intraocular surgery and ocular trauma. after applying the exclusion criteria, 423 patients were studied. le...