The BeEP Server (http://www.embnet.qb.fcen.uba.ar/embnet/beep.php) is an online resource aimed to help in the endgame of protein structure prediction. It is able to rank submitted structural models of a protein through an explicit use of evolutionary information, a criterion differing from structural or energetic considerations commonly used in other assessment programs. The idea behind BeEP (B...

Phenotype-based mutagenesis experiments will increase the mouse mutant resource, generating mutations at previously unmarked loci as well as extending the allelic series at known loci. Mapping, molecular characterization, and phenotypic analysis of nine independent Pax6 mutations of the mouse recovered in mutagenesis experiments is presented. Seven mutations result in premature termination of t...

Neoclassical economics has only recently considered the problem of sustainability—how to provide for the well-being of future generations given ecological constraints. In general, the neoclassical economist perceives physical and ecological constraints on economy-environment interactions as inconveniences that will inevitably be overcome by substitution—the discovery of new economic resources o...

This paper explores the historical relationship between expansion of UK HE system through sectorial diversification, processes differentiation/convergence and (in)equalities since 1960s. It examines extent to which connections tensions three stories resource, mission social differentiations might be influenced (alongside other forces) by emergence crisis successive socio-economic regimes. The e...

The kinetics of substitution of [Ti(ur)6]3+ by H2O and SCN¯ ion in ethanol solution have been measured spectrophotometrically by stopped-flow method. Water is a good nucleophile toward Ti(III) substrates. Even the solvent ethanol appears to be a poor ligand when compared to water. Substitution, in general follows two parallel pathways: "direct" (second order...

Despite the body of research on textbook evaluation from the discourse analysis perspective, cohesive devices have rarely been analyzed in English for Specific Purposes (ESP) textbooks. The acquisition and use of cohesive devices is inherent to naturalistic communication, including business interactions. Hence, L2 learners of business English should be exposed to these devices through cohesion-...

This paper re-examines the conditions under which endogenous economic growth can emerge in neoclassical models with non-renewable resources. Our analysis is based on a general production function encompasses Cobb–Douglas specification. We show that possible only when elasticity of substitution between effective labour input and resource constant equal to one. If this does not hold (as some empi...

This study adds to the scientific literature dealing with climate change mitigation implications of wood substitution. Its main contribution rests modelling approach. By fully integrating forest resource and wood-product markets in quantitative scenario analysis, we account for international trade products as well impacts on EU forests forest-based sector employment an increased uptake wood-bas...