Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target site are the most clinically important and challenging goals in cancer therapy. Liposomes are promising nanocarriers and have been well investigated for cancer therapy. In spite of preferred accumulation in tumors via the enhanced permeability and retention (EPR) effect, inefficient drug release at t...

Motivated by the recent backshoring trend, this paper studies a sourcing game where competing firms may choose between efficient sourcing (e.g., sourcing from overseas) and responsive sourcing (e.g., sourcing from home country). Efficient sourcing usually provides a cost advantage, while responsive sourcing allows a firm to obtain more accurate demand information when making procurement decisio...

Mesoscopic systems - small electric circuits working in quantum regime - offer us a unique experimental stage to explorer quantum transport in a tunable and precise way. The purpose of this Review is to show how they can contribute to statistical physics. We introduce the significance of fluctuation, or equivalently noise, as noise measurement enables us to address the fundamental aspects of a ...

This report is an update of the review for ramp-based baggage handling related literature undertaken in 2005 (Tapley and Riley, 2005). The aim of this review is to present information relating to alternative methods of loading narrow-bodied aircraft that reduce the manual handling related injury and ill-health risks to the handlers, and to identify knowledge gaps. This was used to inform subseq...

Diurnal variation of upper tropospheric humidity and its relations to convective activities over tropical Africa E. S. Chung, B. J. Sohn, J. Schmetz, and M. Koenig School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT), Darmstadt, Germany Received: 20 October 2006 – Accepted: 19 Decem...

Huancayo is the only equatorial electrojet station where the daytime increase of horizontal geomagnetic ®eld (H) is associated with a simultaneous increase of eastward geomagnetic ®eld (Y). It is shown that during the counter electrojet period when DH is negative, DY also becomes negative. Thus, the diurnal variation of DY at equatorial latitudes is suggested to be a constituent part of the equ...

to determine the prognostic value of response to treatment in patients with focal segmental glomerulo-sclerosis. fsgs includes 10-15% of idiopathic nephrotic syndrome in children. bulk of evidence supports disease relationship with immune system. unfortunately, responses to immunosuppressive drugs are not desirable and progression to end-stage renal disease is common. we analyzed 62 out of 99 c...

objective(s): researchers have intended to reformulate drugs so that they may be more safely used in human body. polymer science and nanotechnology have great roles in this field. the aim of this paper is to introduce an efficient drug delivery vehicle which can perform both targeted and controlled antibiotic release using magnetic nanoparticles grafted ph-responsive polymer.  methods: fe3o4 na...