Chung HK, Rathor N, Wang SR, Wang JY, Rao JN. RhoA enhances store-operated Ca entry and intestinal epithelial restitution by interacting with TRPC1 after wounding. Am J Physiol Gastrointest Liver Physiol 309: G759–G767, 2015. First published September 3, 2015; doi:10.1152/ajpgi.00185.2015.—Early mucosal restitution occurs as a consequence of epithelial cell migration to resealing of superficial...

The National Automotive Sampling System/Crashworthiness Database System (NASS/CDS) is a well-known digital repository containing statistics on hundreds of thousands of vehicle crashes that occurred over the past 30 years. Many of the NASS crashes contain estimates of Delta-v calculated using WinSMASH, a common software reconstruction package. Recent work indicates that WinSMASH typically undere...

Jeremy Waldron argues that claims to reparation for historic injustices can be superseded by the demands of justice in present. For example, justified Maori resulting from wrongful appropriation their land European settlers may claim a just distribution resources possessed world’s existing inhabitants. However, if we distinguish between reparative and restitutive claims, see while restitution c...

BACKGROUND Spatially discordant alternans (SDA) has been linked to life-threatening arrhythmias. The mechanisms underlying SDA development in cardiac tissue remain unclear. METHODS AND RESULTS We investigated the role of conduction velocity (CV) restitution and short-term memory in the organization and evolution of alternans in action potential duration using high-resolution optical mapping o...

INTRODUCTION Computer simulations suggest that intercellular coupling is more robust than membrane excitability with regard to changes in and safety of conduction. Clinical studies indicate that SCN5A (excitability) and/or Connexin43 (Cx43, intercellular coupling) expression in heart disease is reduced by approximately 50%. In this retrospective study we assessed the effect of reduced membrane ...