Wang J, Weigand L, Foxson J, Shimoda LA, Sylvester JT. Ca signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho kinase antagonists. Am J Physiol Lung Cell Mol Physiol 293: L674–L685, 2007. First published June 15, 2007; doi:10.1152/ajplung.00141.2007.—Antagonists of myosin light chain (MLC) kinase (MLCK) and Rho kinase (ROK) are thought to inhibit hypoxic pulmon...

Nuclear symmetry energy ${E}_{\text{sym}}(\ensuremath{\rho})$ at density $\ensuremath{\rho}$ is normally expanded or simply parameterized as a function of $\ensuremath{\chi}=(\ensuremath{\rho}\ensuremath{-}{\ensuremath{\rho}}_{0})/3{\ensuremath{\rho}}_{0}$ in the form ${E}_{\text{sym}}(\ensuremath{\rho})\ensuremath{\approx}S+L\ensuremath{\chi}+{2}^{\ensuremath{-}1}{K}_{\text{sym}}{\ensuremath{\...

Given a family $$\varphi = (\varphi_1, \ldots, \varphi_d)\in \mathbb{Z}[T]^d$$ of d distinct nonconstant polynomials, positive integer $$k\le d$$ and real parameter $$\rho$$ , we consider the mean value $$M_{k, \rho} (\varphi, N) \int_{{\rm x} \in [0,1]^k} \sup_{{\rm y} [0,1]^{d-k}} | S_{\varphi}({\rm x}, {\rm y}; |^\rho \,d{\rm $$ of exponential sums $$S_{\varphi}({\rm \sum_{n=1}^{N} \...

A Highlights from MBoC Selection The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation J. van Rijssel, J. Kroon, M. Hoogenboezem, F. P. J. van Alphen, R. J. de Jong, E. Kostadinova, D. Geerts, P. L. Hordijk, and J. D. van Buul 2831–2844 Neutrophils induce endothelial docking structures prior to crossing the blood v...

The fim genetic switch in the chromosome of Escherichia coli K-12 is an invertible DNA element that harbors the promoter for transcription of the downstream fim structural genes and a transcription terminator that acts on the upstream fimE regulatory gene. Switches oriented appropriately for structural gene transcription also allow fimE mRNA to read through, whereas those in the opposite orient...

Background: Chronic oxygen exposure induces pulmonary hypertension in newborn rats. Rho-kinase is upregulated in animal models of hypoxia-induced pulmonary hypertension and Rho-kinase inhibitors decrease the pulmonary arterial pressure. Less is known about the response of Rho-kinase in hyperoxia-induced lung injury in neonates. A rat model of hyperoxia-induced pulmonary injury was established a...

We introduce a generalized additivity of a mapping between Banach spaces and establish the Ulam type stability problem for a generalized additive mapping. The obtained results are somewhat different from the Ulam type stability result of Euler-Lagrange type mappings obtained by H. -M. Kim, K. -W. Jun and J. M. Rassias.

in the present paper, we introduces the notion of integral type contractive mapping with respect to ordered s-metric space and prove some coupled common fixed point results of integral type contractive mapping in ordered s-metric space. moreover, we give an example to support our main result.

Previous genetic analysis showed that the polar effects of mutations in the hisG cistron of Salmonella typhimurium are dependent on the presence of a single putative transcription termination element within the hisG gene. In fact, all proximal mutations causing translation termination are strongly polar, whereas distal ones are not. The element was mapped by isolating mutations able to relieve ...

Let f be an entire function, f(0) = 1, F(z) zf′ (z)/f(z), and Γm $$\bigcup_{j=1}^{m}\left\{z:\mathrm{arg}z={\psi }_{j}\right\},$$ 0 ≤ ψ1 < ψ2 ...< ψm 2π. An function is called a of improved regular growth if for some ρ ∈ (0;+∞) ρ2 (0; ρ), 2π-periodic ρ-trigonometrically convex h(φ) ≢ −∞, there exists set U ⊂ $${\mathbb{C}}$$ contained in the union disks with finite sum radii such that $$\begin{...