The acute haemodynamic efifects of thiopentone, methohexitone and propanidid have been compared in anaesthetized dogs. All three drugs caused a reduction in arterial blood pressure and minor changes in cardiac output, but whereas thiopentone and methohexitone had similar effects propanidid was found to be three times as potent as thiopentone in its effect upon arterial systolic pressure. Thiope...

M-mode echocardiographic features suggesting a patent ductus arteriosus are based on two groups of indirect criteria: dilation of the left cardiac cavities and changes of systolic time intervals. The reliability of the first group of criteria has been questioned in fluid-limited, mechanically ventilated preterm infants. The sensitivity of the systolic time intervals in the same circumstances is...

INTRODUCTION We investigated fluid responsiveness in a population of patients undergoing coronary artery revascularization, with respect to their right ventricular ejection fraction. MATERIALS AND METHODS This was a multicenter trial involving 11 cardiac surgical Institutions and 65 patients undergoing elective coronary artery revascularization. Hemodynamic parameters were measured before and...

OBJECTIVE To test the hypothesis that Vegf-B contributes to the pulmonary vascular remodelling, and the associated pulmonary hypertension, induced by exposure of mice to chronic hypoxia. METHODS Right ventricular systolic pressure, the ratio of right ventricle/[left ventricle+septum] (RV/[LV+S]) and the thickness of the media (relative to vessel diameter) of intralobar pulmonary arteries (o.d...

We investigated the effects of a dual thromboxane (TX)A2 synthase inhibitor and TXA2 receptor antagonist (BM-573) on right ventricular-arterial coupling in a porcine model of endotoxic shock. Thirty minutes before the onset of 0.5 mg/kg endotoxin infusion, six pigs (Endo group) received an infusion with a placebo solution, and six other pigs (Anta group) with BM-573. Right ventricular pressure-...

Although the effects of persistent pressure loading on the development of ventricular hypertrophy have been studied extensively, the effects of intermittent pressure loading have not been examined. To study the effects of intermittent pressure loading we subjected the right ventricle of cats to intermittent pulmonary artery constriction over a 2-week period. Two intermittent pressure loading sc...

conclusions despite the widespread use of 2d lvef and its good agreement with ventriculography, strain analysis seems to be more reliable as a quantitative tool for ventricular assessment. results the lvef values obtained by the two methods of ventriculography and echocardiography were not significantly different. the highest correlation regarding the echocardiographic lvef was obtained in the ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : supervised exercise-based cardiac rehabilitation programs (crp) have been suggested to all patients, especially after myocardial infarction. however, the effects of cardiac rehabilitation on systolic function are controversial. the aim of this study was to examine the effects of an 8-week cardiac rehabilitatio...

OBJECTIVE To examine the effects of pacing modes on the interaction between the left ventricle and arterial system in humans. DESIGN The slope of the end systolic pressure-volume relation (end systolic elastance), effective arterial elastance, the ratio of effective arterial elastance to end systolic elastance, and mechanical energy efficiency were compared under different pacing modes (atria...

Methods We included 139 patients undergoing CMR and right heart catheterization within 2 days (n=151 test pairs) for the evaluation of known or suspected pulmonary hypertension. Right ventricular end-systolic volume index (ESVI) and stroke volume index (SVI) were obtained, respectively, from cardiac cine images and phasecontrast of the pulmonary artery after adjusting for body surface area. Rig...