objective: mindfulness skills are assumed to be related with emotions. deficits in emotion ‎regulation could lead to development and persistence of mood disorders. dysthymia and double ‎depression are two chronic types of depression. this chronicity can be attributed to the one’s ‎inability to regulate his/ her mood. in this study, we aimed to evaluate the effect of mindfulness-‎based cognitive...

introduction: the present study aims at determining the efficacy of family based cognitive-behavioral therapy on children's anxiety. methods: in a quasi-experimental study, 120 girls’ with the ages of 10-11 with scores above 24 on the spence children's anxiety scale were enrolled. the mothers completed the spence children's anxiety scale-parent version. mothers and children were randomly assign...

Evaluation of gene expression in urinary sediment has been considered as a promising non-invasive approach for biomarker identification of kidney diseases. Nonetheless, there are several challenges in extraction of RNA from this valuable source of biomarkers, mostly because of the factors that have influence on quality of isolated RNA such as low cellular content. Accordingly, we compared the q...

micrornas are tiny, 18-25 nucleotides in length, non-coding rna molecules preserved throughout evolution. these molecules primarily control gene expression at the post-transcriptional and transcriptional levels. micrornas control target gene expression by a phenomenon known as rna interference. rna interference based therapeutics that utilize target gene silencing/degradation by specific micror...

Background: Hepatitis C virus (HCV) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. In this study we aimed to evaluate the effects of pegylated interferon alfa-2a (PEG-IFN A-2a) in reducing serum ALT and eradicating serum hepatitis C virus (HCV) RNA in HCV infected polytransfused thalassemic patients. Materials and Methods: A cohort of 51 HCV-...

aim and background: efficacy of mindfulness based cognitive therapy and traditional cognitive behavior therapy in reduction of over generality in autobiographical memory test of patients with major depressive disorder in 2007 is considered in this study. method and materials: this clinical-experimental study was carried out on 90 patients randomly selected from 160 cases refering to tehran univ...

background: the herpes simplex virus (hsv) ul41 gene product, virion host shutoff (vhs) protein, mediates the rapid degradation of both viral and cellular mrna. this ability suggests that vhs protein can be used as a suicide gene in cancer gene therapy applications. the recent reports have shown that the degradation of cellular mrna during herpes simplex infection is selective. rna containing a...

objectives: the present research has been carried out to investigate the effectiveness of group mindfulness-based cognitive therapy on modification of body image and quality of life in women with breast cancer undergoing mastectomy.  materials: this research is a quasi-experimental study (pretest-posttest with control). in this clinical trial, 50 voluntary patients who had undergone mastectomy ...