not understand how she came to have parents so entirely different from herself. Spurred by various emotional urges she sets out on a crusade to '' live her own life.'' Usually she discovers herself inadequate to meet life as independently as she would like. She finds also that the consequences of independence are somewhat staggering. It is difficult to understand how anyone who has worked with ...

MOTIVATION We present a new probabilistic model of the evolution of RNA-, DNA-, or protein-like sequences and a software tool, Rose, that implements this model. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and substitution of characters. During this artificial evolutionary process, the 'true' history is logged an...

Electronic excitation of a probe chromophore can lead to a change in dipole moment that influences its activity or solubility in solution and changes its relative affinity for partitioning between two phases. Photoexcitation of a probe molecule can, therefore, perturb a sorption equilibrium, and the relaxation kinetics of the probe to the new equilibrium conditions can be monitored in a time-re...

BACKGROUND Over decades, evidence has accumulated to justify the concern that top-down approaches do not work and may result in lack of program ownership and sustainability. As a result, participatory approaches have increasingly become popular. An example of such an approach is hereby presented. DESCRIPTION Working with AMREF, Mkuranga district significantly gained experience and improved it...

We studied the effect of converting enzyme inhibition with enalapril on the natriuresis observed after administration of atrial natriuretic factor (human ANF-[99-126], given as a 100-micrograms bolus i.v. injection) in eight healthy humans consuming a 100 mmol sodium diet. Without enalapril, sodium excretion rose from 127 +/- 19 (mean +/- SE) to 437 +/- 103 mumol/min in the first 20 minutes aft...

The stopped-flow mixing technique was used to develop a very fast, sensitive and accurate method for determining total proteins. The method is based on the lower fluorescence of Rose Bengal caused by binding of the dye to the proteins. The decrease in the fluorescence intensity, measured at 572 nm with excitation 555 nm, was linearly related to protein concentration from 1.3 to 24.5 micrograms ...

We studied whether the biomechanical properties of brain play an important role in the development of early ischemic brain edema in cats with middle cerebral artery occlusion. Brain tissue pressure, tissue compliance, and tissue resistance were measured from the gray matter in the core and the periphery of the middle cerebral artery territory for 6 hours after occlusion. Regional cerebral blood...

BARGER, A. C., F, E, YATES AND A. M. RUDOLPH. Renal hemodynumics and sodium excretion in dogs with graded valvular dumige, and in congestive failure. Am. J. Physiol. 200(3) : 601-608. 1961 .-In an attempt to study the sequence of renal changes which occur with progressive cardiac impairment, renal plasma flow, glomerular filtration rate, sodium and water excretion were investigated in a group o...