BACKGROUND Liver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in order to study their biological effects is to search in ancient medical texts. Avicenna who is known ...

A Balaton déli partmelléke és a háttérterületén emelkedő Külső-Somogy dombvidék célzott flóra- vegetációkutatása eredményeképp jelen közleményben 230 edényes növénytaxon feltérképezett előfordulási adatait mutatom be. Növényföldrajzi szempontból kiemelkedő jelentőségű Dél-Dunántúlról eddig ismeretlen Vicia sparsiflora előkerülése. E faj lösz dombhátain jellemző más xerotherm tölgyes elemek (Car...

INTRODUCTION A medical visit for plant ingestion is rare in the pediatric emergency services but may involve a high toxicity. The botanical toxicology training of health staff is often very limited, and it can be difficult to make a diagnosis or decide on the appropriate treatment. OBJECTIVE To study the epidemiological and clinical characteristics of poisoning due to plant ingestion in order...

The Drosophila spineless (ss) gene encodes a basic-helix-loop-helix-PAS transcription factor that is required for proper specification of distal antennal identity, establishment of the tarsal regions of the legs, and normal bristle growth. ss is the closest known homolog of the mammalian aryl hydrocarbon receptor (Ahr), also known as the dioxin receptor. Dioxin and other aryl hydrocarbons bind ...

Eukaryotic evolution has been characterized by intron loss. In eukaryotes, the proposed mechanisms of intron loss are exonization, random genomic deletion, retroprocessing and most recently, horizontal gene transfer followed by gene conversion (HGT-GC). Here we investigate the mechanism of intron loss from the mitochondrial cox2 gene, which in previous studies has shown a variable intron distri...

Drug development regularly has to deal with complex circumstances on two levels: the local level of pharmacological intervention on specific target proteins, and the systems level of the effects of pharmacological intervention on the organism. Different development strategies in the recent history of early drug development can be understood as competing attempts at coming to grips with these mu...