saffron, the dried red-orange stigmas of crocus sativus l, has been known as a flavoring agent, food coloring and traditional herbal medicine. pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. these components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...

Saffron (Crocus sativus) merupakan tumbuhan yang dapat digunakan sebagai obat tradisional dan juga dalam produk olahan makanan. Bahan aktif saffron, seperti flavonoid, saponin, tanin, diketahui senyawa antibakteri. fermentasi yoghurt berperan prebiotik untuk zat terkandung yoghurt, yaitu bakteri asam laktat (BAL). Bakteri patogen menyebabkan beberapa penyakit, diantaranya Pseudomonas aeruginosa...

The aim of this study was to evaluate the anti-nociceptive effects of a low, sub-effective dose of amitriptyline, in combination with the different doses of ethanolic and aqueous extracts of Crocus sativus following sciatic nerve chronic constriction injury (CCI) in rats. Amitriptyline (3, 10 and 30 mg/Kg, i.p.) and the extracts (25, 50 and 100 mg/Kg, i.p.), were separately administered at the ...

From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...

background & aim: saffron extract is widely used in the food industry. saffron (crocus sativus l.) stigmata contain rare water-soluble carotenoids and the major one is crocin and this compound have a antitumor in rate and human losomi cells and other model of cancer cells.  in this research, we are study on effects of cultivation condition and storage on dried stigmata of   crocus sativus l...

this study was designed to investigate the therapeutic effects of saffron (crocus sativus l) and its main constituent crocin on neuropathic pain behavioral responses induced by chronic constriction injury (cci) in rats. adult male wistar rats (200 to 250 g) were randomly assigned into 5 groups: sham + saline, cci + saline, cci+ saffron (30 mg/kg), cci +crocin (15 mg/kg) and cci + crocin (30 mg/...

Tissue culture is useful method for large scale production of healthy corms and also avenues for creating variability through in vitro use of mutagens and polyploidizing agents. Induction of callus and subsequent regeneration of plants is suggested as possible means of introducing new variation. In vitro micropopagation for product formation its utility is increasing the amount of crocin, picro...

Stigma of Crocus sativus L. (Iridaceae), commonly known as saffron, is the world’s most expensive spice and apart from its traditional value as food additive recent studies indicate its potential as antidepressant. Because saffron is expensive, using it daily to address depression may not be practical. Moreover, recent study indicated antidepressant effect of petal of Crocus sativus. As petal o...

safranal, the main component of crocus sativus essential oil, is thought to be the main cause of saffron unique odor. it is now about eighty years that this compound has been discovered and since then different scientific experiments have been done investigating its biological-pharmacological activities. safranal effects in cns have been more attractive to scientists and an escalating number of...