BACKGROUND Over the past 10 years, the use of saliva as a diagnostic fluid has gained attention and has become a translational research success story. Some of the current nanotechnologies have been demonstrated to have the analytical sensitivity required for the use of saliva as a diagnostic medium to detect and predict disease progression. However, these technologies have not yet been integrat...

Total plasma and mixed stimulated saliva theophylline concentrations (by high performance liquid chromatography) and free plasma theophylline concentrations (by equilibrium dialysis) were measured in simultaneously collected samples from 32 outpatients receiving chronic oral theophylline treatment, who had received the drug at least two hours before sampling. There was a close relationship betw...

The lithium ions concentration in human serum and saliva was determined using dry-slide technology Vitros 250 Analyser (Ortho Clinical Diagnostic) and atomic absorption spectrometry Perkin Elmer 403 (AAS). We analyzed lithium ions in 100 serum and saliva specimens of patients after oral administration of lithium carbonate (3 x 300 mg) Jadran, Galen Laboratory Rijeka. Saliva and blood were taken...

The purpose of this in vitro study was to evaluate microleakage of two fluoride-releasing sealants in saliva contaminated and non-contaminated conditions. Twenty-four human third molars were randomly assigned to two groups: saliva contaminated and saliva non-contaminated teeth. In the contaminated group, the teeth were contaminated with 0.02 ml artificial saliva for 20 seconds and blowed dry af...

The spinnbarkeit of saliva reflects the ability of saliva to adhere to surfaces within the mouth, thereby serving as a protective role and aiding in lubrication. Therefore, alterations in the extensional rheology of saliva may result in the loss in adhesiveness or the ability to bind onto surfaces. Mucin glycoproteins and their structures are known to be important factors for the extensional rh...

Introduction: Recent studies point to the clinical and research efficacy of saliva as a respected diagnostic aid for observing Multiple Sclerosis. The objectives of this Hypothesis are to identify novel biomarkers recognized to Multiple Sclerosis in early stage in saliva and to determine if the levels of these markers correlate with level of these Cerebrospinal fluid and blood assays and urine ...

Fourier Transform Mid-Infrared spectroscopy with Attenuated Reflection combined with multivariate data Principal Component Analysis have been applied for the discrimination of 12 couples of resting and stimulated saliva obtained from healthy volunteers. The resting saliva samples were collected before eating, while stimulated saliva, after chewing stimulation with parafin and preserved in Natri...

pure submandibular saliva was collected from anaesthetized vitamin - a - treated and control rats with using of pilocarpine as secretogogue, and then the serum was collected by cardiac puncutre. intraperitoneal injection of a large single dose (100,000 iu/kg) of vitamin a changed total protein, calcium and sodium concentrations of saliva so that sodium level of submandibular saliva was reduced ...