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Acne vulgaris is a common disease that carries an enormous financial and psychosocial impact. Androgens, excessive sebum production, ductal hypercornification, changes in the microbial flora, as well as inflammation and immunological host reactions are considered the major contributors to acne pathogenesis. Despite extensive research on acne pathogenesis, the exact sequence of events and their ...

The challenge for the development of next generation software is the successful management of the complex grid environment while delivering to the scientist the full power of flexible compositions of the available algorithmic alternatives. Self-Adapting Numerical Software (SANS) systems are intended to meet this significant challenge. A SANS system comprises intelligent next generation numerica...

The role of small-angle x-ray and neutron scattering (SAXS and SANS) in the characterization of cement is briefly reviewed. The unique information obtainable from SANS analysis of C-S-H gel in hydrating cement is compared with that obtainable by other neutron methods. Implications for the nature of C-S-H gel, as detected by SANS, are considered in relation to current models.

The human Usher syndrome (USH) is the most frequent cause of combined hereditary deaf-blindness. USH is genetically heterogeneous with at least 11 chromosomal loci assigned to 3 clinical types, USH1-3. We have previously demonstrated that all USH1 and 2 proteins in the eye and the inner ear are organized into protein networks by scaffold proteins. This has contributed essentially to our current...

Psychotherapy which dominated psychiatry for long seems to have become relegated into oblivion. Whether this change in the professional practice is a progressive or re-trograde step requires a serious consideration. Psychiatrists in India are more or less practising a biologic reductionistic model of mental illness and if this trend continues they may become manque neurologists. Having been ass...

With the increase popularity of online education, the task of providing the right information to the right users has become a real challenge. Adaptive Hypermedia has been established as one solution to this challenge. However, many adaptation techniques are well suited for closed-corpus and are not compatible in open-corpus situation. Our solution for open-corpus adaptive navigation support is ...

Le syndrome de Poland correspond à l'absence ou l'hypoplasie unilatérale du grand pectoral associée à des anomalies homolatérales de la main, le plus souvent une symbrachydactylie. Garçon âgé de 5 ans, issu d'un mariage non consanguin et d'une grossesse de déroulement normal sans notion de prise médicamenteuse par la mère. A la naissance, la malformation au niveau de la main gauche a été décelé...