Sesquiterpenes lactones including costunolide and dehydrocostus lactone, were isolated from Saussurea lappa roots, which had exhibited a wide range of biological activities such as anti-cancer, anti-inflammatory, antiulcer, and immunomodulatory activities. High-speed counter-current chromatography (HSCCC) was applied for the rapid preparative isolation of sesquiterpenes lactones from <...

The traditional Chinese medicine component dehydrocostuslactone (DHC) isolated from Saussurea costus (Falc.) Lipschitz, has been shown to have anti-cancer activity. Angiogenesis is an essential process in the growth and progression of cancer. In this study, we demonstrated, for the first time, the anti-angiogenic mechanism of action of DHC to be via the induction of cell cycle progression at th...

The moist temperate Himalayas, as one of the major ecological zone of Pakistan, deserve specific attention to the conservation of environment and the sustainable development of natural resources. During the last hundred years, the area has been subjected to major structural changes leading to a decrease of about fifty per cent of the potential forest area. The decrease in forest cover, combined...

The moist temperate Himalayas, as one of the major ecological zone of Pakistan, deserve specific attention to the conservation of environment and the sustainable development of natural resources. During the last hundred years, the area has been subjected to major structural changes leading to a decrease of about fifty per cent of the potential forest area. The decrease in forest cover, combined...

This article reports the results obtained from a study of the usefulness of Saussurea Lappa on the treatment of Ichaemic Heart Diseases.

We estimate phylogenetic relationships and the biogeographic and pollination history of Costus subgenus Costus (Costaceae) using sequence data from the internal and external transcribed spacer (ITS and ETS) regions of 18S-26S nuclear ribosomal DNA. The African members of the subgenus form a series of lineages basal to a monophyletic neotropical species radiation. The neotropical species have la...

This article documents the addition of 139 microsatellite marker loci and 90 pairs of single-nucleotide polymorphism sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Aglaoctenus lagotis, Costus pulverulentus, Costus scaber, Culex pipiens, Dascyllus marginatus, Lupinus nanus Benth, Phloeomyzus passerini, Podarcis muralis, Rhododendron...

Costus Igneus (insulin plant) traditionally used medicinal herb which is native to southeast Asia. The plant has been recently introduced into india and it grow as ornamental in south India. India insulin contain various phytochemicals constituent llike steroid, alkaloid , flovonoid, Triepene, glycoside saponins. Its leaves are dietary supplement treatment of diabetes mellitus. catchphrase the ...