One-on-one tutoring is a form of instruction that requires interaction between a tutor and a tutee. The effectiveness of tutoring is examined from the perspectives of the tutor's actions, the tutee's actions, and successive interactions. A tutor's actions that may not lead to successive interactions consist of asking an initiating question, providing feedback, and asking a comprehension-gauging...

Teachers often perceive educational research as confusing and can be disenfranchised by the research process. We propose scaffolded authethnography as a method to support principled examination of authentic practice. The approach is appealing because it is motivated by the teacher’s own day-to-day practice in a research context. Our demonstration of this method uses an analytical autoethnograph...

Adaptive navigation support can be of great help in large hypermedia systems supporting learners as well as users searching for specific information. A wide variety of adaptive mechanisms have been implemented in existing adaptive hypermedia systems that provide better and better suggestions to the user what hyperlinks to follow. We suggest that adaptive navigation support should scaffold a lea...

A conceptually new approach to the design of macromolecular receptors for lectins is outlined. Carbohydrate-functionalised Polymer-Scaffolded Dynamic Combinatorial Libraries (PS-DCLs) have been prepared in aqueous solution by the reversible conjugation of carbohydrates possessing acylhydrazide functionalities in their aglycone on to an aldehyde-functionalised polymer scaffold. PS-DCLs have been...

Membrane scission is essential for intracellular trafficking. While BAR domain proteins such as endophilin have been reported in dynamin-independent scission of tubular membrane necks, the cutting mechanism has yet to be deciphered. Here, we combine a theoretical model, in vitro, and in vivo experiments revealing how protein scaffolds may cut tubular membranes. We demonstrate that the protein s...

Synthetic DNA is a highly programmable nanoscale material that can be designed to self-assemble into 3D structures that are fully determined by underlying Watson-Crick base pairing. The double crossover (DX) design motif has demonstrated versatility in synthesizing arbitrary DNA nanoparticles on the 5-100 nm scale for diverse applications in biotechnology. Prior computational investigations of ...