henoch-schönlein purpura nephritis and iga nephropathy are currently considered to be different clinical presentations of the same disease. there is need for a reliable proven, morphologic classification that can help clinicians more accurately formulate treatment strategies for patients with henoch-schönlein purpura nephritis. considering that henoch-schönlein purpura nephritis and iga nephrop...

Henoch-Schönlein purpura is the most common systemic vasculitis of childhood. In the majority of children, the outcome of Henoch-Schönlein purpura is excellent with spontaneous resolution of symptoms and signs. However, a small subset of patients will develop long-term sequelae in the form of chronic kidney disease. While the clinical presentation and diagnosis of Henoch-Schönlein purpura is st...

Henoch-Schönlein purpura nephritis and IgA nephropathy are currently considered to be different clinical presentations of the same disease. There is need for a reliable proven, morphologic classification that can help clinicians more accurately formulate treatment strategies for patients with Henoch-Schönlein purpura nephritis. Considering that Henoch-Schönlein purpura nephritis and IgA nephrop...

The gastrointestinal manifestations of Henoch-Schönlein purpura include abdominal pain, gastrointestinal bleeding, intussusception, and perforation. Protein-losing enteropathy is rarely associated with Henoch-Schönlein purpura. Two pediatric patients with Henoch-Schönlein purpura who developed protein-losing enteropathy are reported. Tc-99m human serum albumin scintigraphy is useful in the dete...

INTRODUCTION Henoch-Schönlein purpura is an immunoglobulin A-mediated, small vascular inflammatory disease that can be associated with palpable purpura, arthralgia, abdominal pain, or nephritis. The presence of purpura facilitates the diagnosis of Henoch-Schönlein purpura at the onset of associated symptoms, whereas the absence of purpura makes the diagnosis challenging. It is important to diag...

INTRODUCTION Henoch-Schönlein purpura is a small-vessel systemic vasculitis. Although its exact pathophysiology remains unknown, Henoch-Schönlein purpura has been reported in association with various medical conditions including hypersensitivity. We report the case of a patient with vancomycin-induced Henoch-Schönlein purpura. CASE PRESENTATION A 42-year-old Caucasian man who had previously u...

BACKGROUND Glomerular deposition of IgA1 is a common feature of Henoch-Schönlein purpura, and is indistinguishable from that seen in IgA nephropathy. Serum IgA1 is abnormally O-glycosylated in IgA nephropathy, and this may contribute to mesangial IgA1 deposition and the development of glomerular injury. This altered O-glycosylation of IgA1 can be detected by its increased binding to the lectin ...

disorders. J Rheum 1992; 19: 721–28. 2 Mills JA, Michel BA, Bloch DA, et al.The American College of Rheumatology 1990 criterial for classification of Henoch-Schönlein purpura. Arthr Rheum 1990; 33: 1114–21. 3 Tancrede-Bohin E, Ochonisky S,Vignon-Pennamen M, Flaheul B, Morel P, Rybojad M. Henoch-Schönlein purpura in adult patients. Arch Dermatology 1997; 133: 438–42. 4 Blanco R, Martinez-Taboada...

INTRODUCTION Henoch-Schönlein purpura is a systemic disease with frequent renal involvement, characterized by IgA mesangial deposits. Streptococcal infection can induce an abnormal IgA immune response like Henoch-Schönlein purpura, quite similar to typical acute post-infectious glomerulonephritis. Indeed, hypocomplementemia that is typical of acute glomerulonephritis has also been described in ...

The most common urological manifestation of Henoch-Schönlein purpura is focal proliferative glomerulonephritis. Ureteric obstruction as a consequence of the disease has been reported in children but is rare. We report an adult male patient with Henoch-Schönlein purpura causing unilateral, bi-focal, recurrent ureteric obstruction. We speculate that ureteric involvement in Henoch-Schönlein purpur...