A number of thiazole derived tridentate Schiff-bases (LH) and its metal chelates of the type [M(L)(2)X] where M=Ni(II), Cu(II) and Zn(II), L=substituted salicylaldehyde (5-H, 5-CH(3), 5-OCH(3), 5-NO(2) and 5-Cl) and X=CI have been synthesized and characterized with the help of elemental analyses, conductivity measurements, magnetic moments, UV-Vis, IR and NMR spectral data. An octahedral struct...

The Schiff bases HL(1-3) have been prepared by the reaction of 5-bromothiophene-2-carboxaldehyde with 4-amino-5-mercapto-3-methyl/propyl/isopropyl-s-triazole, respectively. Organosilicon(IV) and organotin(IV) complexes of formulae (CH(3))(2)MCl(L(1-3)), (CH(3))(2)M(L(1-3))(2) were synthesized from the reaction of (CH(3))(2)MCl(2) and the Schiff bases in 1 : 1 and 1 : 2 molar ratio, where M = Si...

The copper-catalyzed [3+2] azide-alkyne cycloaddition and the Staudinger ligation are readily applicable and highly efficient for the immobilization of cobalt Schiff base complexes onto polystyrene resins. Stepwise synthesis of polymer-bound Schiff bases followed by their subsequent complexation with metal ions were successfully carried out. Direct covalent attachment of preformed homogeneous c...

Metal chelates of Schiff base prepared by combining salicylaldehyde and amino acids could be effectively used in understanding the mechanism of transamination reaction. They can act as biomimetic species. The current article focused on the syntheses, characterization, complexation behaviour and antimicrobial studies of some novel Schiff bases formed from salicylaldehyde with 3-amino benzoic aci...

To get inside the properties of N,N-disubstituted Schiff bases, we synthesized three high-yielding benzaldehyde Schiff bases. We used the reaction between salicylaldehyde and different diamine compounds, including diamine, ethanediamine, and o-phenylenediamine, determining the structure of obtained molecules by nuclear magnetic resonance spectroscopy and electrospray ionization mass spectroscop...

Schiff bases and their metal-complexes are versatile compounds exhibiting a broad range of biological activities and thus actively used in the drug development process. The aim of the present study was the synthesis and characterization of new Schiff bases and their copper (II) complexes, derived from L-tryptophan and isomeric (2-; 3-; 4-) pyridinecarboxaldehydes, as well as the assessment of t...

BACKGROUND Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were synthesized and screened for its antimicrobial and anticancer potentials. The molecular docking study was carried to find the interaction between active molecules with receptor....