OBJECTIVE It is known that there is a high prevalence of certain anxiety disorders among schizophrenic patients, especially panic disorder and social phobia. However, the neural underpinnings of the comorbidity of such anxiety disorders and schizophrenia remain unclear. Our study aims to determine the neuroanatomical basis of the co-occurrence of schizophrenia with panic disorder and social pho...

In this study first published in 1972, 218 relatives of 28 schizophrenic and a control group of 34 brain-damaged patients were interviewed and tested with the original Rorschach inkblot cards. In contrast to Rorschach surveys in the general population, the study revealed schizophrenia-like test results in approximately one quarter of the subjects, equally distributed among the relatives of schi...

Some genetically determined traits, such as ear lobes, finger hair and hairy car were studied in 89 schizophrenic patients and compared with normals. The proportion of schizophrenic males having earlobes hanging free was much less than the control group. This difference is highly significant statistically (p < .0001). Similar was our observation in schizophrenic females (p < .05). Furthermore n...

BACKGROUND Abnormal connectivity of the anticorrelated intrinsic networks, the task-negative network (TNN), and the task-positive network (TPN) is implicated in schizophrenia. Comparisons between schizophrenic patients and their unaffected siblings enable further understanding of illness susceptibility and pathophysiology. We examined the resting-state connectivity differences in the intrinsic ...

BACKGROUND The importance of neuronal interactions in development, the cortical dependence of many thalamic nuclei, and the phenomenon of transsynaptic degeneration suggest possible abnormalities in thalamic nuclei with connections to other brain regions implicated in schizophrenia. Because frontal and temporal lobe volumes are diminished in schizophrenia, volume loss could characterize their p...

The existence of a restrained inflammatory state in schizophrenic individuals posed the question whether anti-inflammatory drugs may exert antipsychotic effects. Therefore, the effect of ibuprofen (IB) on cytokine production by human peripheral blood mononuclear cells (PBMC) from schizophrenic patients was examined and compared to that of healthy subjects. PBMC from 25 schizophrenic patients an...

To examine the neurophysiological and cognitive characteristics of thought disturbance in schizophrenic patients, we examined the amplitude, latency, and topography of a specific event-related brain potential (ERP), the N400, which is elicited by semantically incongruent words and phrases. Twelve chronic schizophrenic patients and twelve age-matched control subjects read sentences presented vis...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : schizophrenia requires a large share of medical resources due to its early onset and chronic and severe nature. compliance therapy is a therapy specifically designed to improve concordance with treatment for those with major mental illnesses. the aim of present study was to determine whether compliance therapy...