objective: to assess the effect of heparin binding neurotrophic factor (hbnf) on sciatic nerve regeneration in animal model of rat. methods: seventy-five male wistar rats were divided into five experimental groups randomly (each group containing 15 animals): sham operation group (sham), autograft group (auto), transected control (tc), chitosan conduit (chit) and heparin binding neurotrophic fac...

the nervous system has an important and vital role in the human body, but unfortunately the repairment of damaged nervous tissue is very slowly. for a long time, the scientists have been involved in finding ways to speed up this process. radiation of low power he-ne laser has been suggested to as a way to improve this issue. in this study, 20 rats were divided randomly into control and case gro...

objective (s): scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. this study evaluates the translational capacity of four of physical injury models to induce scar formation around the sciat...

background: initial studies have shown that low-energy ultrasound stimulates living tissue cells to reduce regeneration or speed up their recovery. the purpose of this study was to examine the effects of various ultrasound parameters on the speed of recovery in injured sciatic nerves. methods: nmri mice (n = 200) with injured left paw, caused by crushing their sciatic nerves, were randomly sele...

to evaluate the effects of local administration of the fetal brain extract (fbe) on the crushed peripheral nerve, 15 male wistar rats were used. the right sciatic nerve of 10 rats was locally underwent the tense compression for 30 seconds and then randomly divided into experimental and control (sham) groups. the remained rats were considered as intact animals. treatment was commenced weekly, by...

conclusions our anesthesia method was sciatic and femoral nerve block under double ultrasonic and nerve stimulator guidance. case presentation in this case report, we present a patient who had tibia and fibula fractures and a symptomatic severe critical aortic stenosis which was diagnosed during a preoperative visit. the patient had exertional dyspnea, palpitations and fainting history, but he ...

excessive scarring; paralleling the process in tendon reconstruction of the hand. inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. methods:  thirty female rats (~200 g) were randomly distributed into two groups (n=15...

objective(s): crocin is a constituent of saffron and has many biological functions. the present study aimed to investigate the effects of intraperitoneal (ip) injection of crocin on sciatic nerve regeneration in male wistar rats. materials and methods: fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...

how to cite this article: toopchizadeh v, barzegar m, habibzadeh a. sciatic nerve injection palsy in children, electrophysiologic pattern and outcome: a case series study. iran j child neurol. summer 2015;9(3):69-72. abstract sciatic nerve injury is one of the frequent mononeuropathies in children that occurs due to different causes such as nerve compression, trauma and stretch during surgery. ...

Peripheral nerve injury requires a long recovery period, and recovery, once attained, usually is incomplete. Inflammatory procedures may inhibit functional recovery after nerve injury and produce cell death in both the central nervous system and the peripheral nervous system. Since the glycyrrhiza glabra extract has anti-inflammatory effects, it could reduce the severity of injury. The aim of t...