Background: The pressures of medical school can be extremely difficult for personal wellness and contribute to anxiety, burnout depression. High demands academic performance restraints extracurricular activities all add distress a student. Methodology: A cross sectional study using convenient sampling was carried out in students CPMC, Lahore. sample size 208 taken. data collected the SF-36 ques...

Hubble Space Telescope images of the core-collapse supernova remnant Cassiopeia A are used to identify highvelocity knots of ejecta located outside the remnant’s main emission shell of expanding debris. These ejecta fragments are found near or ahead of the remnant’s forward shock front and mostly lie from 12000 to 30000 in radial distance from the remnant’s center of expansion. Filter flux rati...

pharaoh cuttlefish (sepia pharaonis) is commercially important and native cephalopods in the persian gulf and oman sea. in 2013, a total of 150 eggs of pharaoh cuttlefish were collected from 20 m depth in about 6 miles south of lengeh port and transferred to the laboratory of mollusks research station in bandar-e lengeh. eggs were incubated in temperature of 27.5±0.5 0c (mean ± sd) and salinity...

The aim of this study was to further characterize the expression and function of human CYP2B6 in a recently generated CYP2A13/ 2B6/2F1-transgenic (TG) mouse model, in which CYP2B6 is expressed selectively in the liver. The inducibility of CYP2B6 by phenobarbital (PB) and dexamethasone (DEX), known inducers of CYP2B6 in human liver, was examined in the TG mice, as well as in TG/Cyp2abfgs-null (o...

1a,25-Dihydroxyvitamin D3 [1,25(OH)2D3] concentrations are regulated by renal CYP27B1 for synthesis and CYP24A1 for degradation. Published plasma and tissue 1,25(OH)2D3 concentrations andmRNA fold change expression of Cyp24a1 andCyp27b1 following repetitive i.p. injections to C57BL/6 mice (2.5 mg 3 kg every 2 days for 4 doses) were fitted with a minimal and full physiologically-based pharmacoki...

Salmonellosis, campylobacteriosis and listeriosis are food-borne diseases. We estimated and forecasted the number of cases of these three diseases in Belgium from 2012 to 2020, and calculated the corresponding number of disability-adjusted life years (DALYs). The salmonellosis time series was fitted with a Bai and Perron two-breakpoint model, while a dynamic linear model was used for campylobac...

IMPORTANCE This study confirmed the long-term outcomes of the ZB5M phakic intraocular lens (PIOL). OBJECTIVE To evaluate the potential long-term risk associated with ZB5M PIOL implantation. DESIGN, SETTING, AND PARTICIPANTS A retrospective, nonrandomized, consecutive cohort study of a total of 208 eyes implanted with ZB5M PIOLs at VISSUM Corporación Oftalmológica de Alicante between 1990 an...

Alprostadil (prostaglandin E1) administration to liver transplant recipients has been shown to result in a significant reduction in the duration of hospital admission for transplantation, and in the need for re-operations (other than re-transplants) and renal support. To study the economic impact of this finding, we examined data from a controlled trial for all single-transplant surviving patie...