Large supraphysiologic transmembrane electrical potentials are known to alter the molecular organization of the bilayer lipid component of cell membranes, leading to ionic permeabilization or "electroporation". Typically, membrane electroporation is followed by several orders of magnitude increases in electrical conductance and diffusive permeability to low-molecular-weight solutes. Electropora...

This study analyzes soil sealing and its repercussions in the loss of fertile soils, which are more appropriate for agriculture use. Also, soil sealing increases flood risk. The main objective is to estimate soil loss by sealing in the Guadarrama River Basin (Madrid, Spain) between 1961 and 2011. The combination of digital processing (Normalized Difference Vegetation Index (NDVI), principal com...

Bone remodeling is dependent on the dynamic equilibrium between osteoclast-mediated bone resorption and osteoblast-mediated osteogenesis. The sealing zone is an osteoclast-specific cytoskeletal structure, the integrity of which is critical for osteoclast-mediated bone resorption. To date, studies have focused mainly on the osteoprotegerin (OPG)‑induced inhibition of osteoclast differentiation t...

BACKGROUND Percutaneous endoscopic lumbar discectomy is a common surgical treatment for lumbar disc herniation, and percutaneous endoscopic interlaminar lumbar discectomy (PEID) is commonly used for direct decompression of L5-S1. Like microdiscectomy, recurrence of herniation after endoscopic discectomy is an important problem. In this study, we aimed to decrease the recurrence after PEID using...

A pipeline inspection gauge (PIG) is routinely passed throughout the long-distance oil and gas pipelines by operators to clean pipeline. Sealing performance a significant evaluation index for PIG's safety operation. To comprehensively evaluate seal performance, nonlinear finite element models were developed, parametric analysis was conducted in this study. The accuracy of simulation model valid...

To solve the problem of field application downhole hydraulic fracturing technology due to difficulty in sealing holes, this study analyzes influence special cement, expansion agents, stabilizers, and fiber material on basic properties, such as setting time, fluidity, compressive strength high-pressure materials through systematic tests based a summary conventional materials. It was determined t...

Pressure balance control between steel sleeve fillings and stratum is the key to ensuring project safety in receiving construction of subway shield tunnels. Here, realize active regulation filing pressure sleeve, this study first improves fixed cover a conventional piston that can slide freely along longitudinal direction puts forward corresponding methods for hydraulic mechanical regulation. T...

This paper reports the feasibility of optical coherence tomography (OCT) technology for inspection of bonding quality of microfluidic devices in manufacturing environments. A compact optical-fiber-based OCT is developed and its measurement performance is characterized. A series of microfluidic devices respectively bonded by adhesive tape, thermal method, and oxygen plasma, are inspected. The de...